CaMKIIα/δ (phospho Thr286) Polyclonal Antibody

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商品货号： PLP000041

适应性： 人,小鼠,大鼠,猪

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CAMK2A/CAMK2D
蛋白名称： Calcium/calmodulin-dependent protein kinase type II subunit alpha/delta
Human_gene_id： 815/817
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=815
Human_swiss_prot_no： Q9UQM7/Q13557
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UQM7/entry
Mouse_gene_id： 12322/108058
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12322
Rat_gene_id： 25400/24246
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25400
Rat_swiss_prot_no： P11275/P15791
Rat_swiss_link： http://www.uniprot.org/uniprot/P11275
特异性： Phospho-CaMKIIα/δ (T286) Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein only when phosphorylated at T286.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II
实测条带： 54kD
信号通路： ErbB_HER;Calcium;Oocyte meiosis;WNT;WNT-T CELLLong-term potentiation;Neurotrophin;Olfactory transduction;GnRH;Melanogenesis;Glioma;
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Postsynaptic lipid rafts.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .
组织表达： Brain,
科研货号： PLP000041

CaMKIIα/δ (phospho Thr286) Polyclonal Antibody

Catalog No PLP000041

Product information

基因名称： CAMK2A/CAMK2D
蛋白名称： Calcium/calmodulin-dependent protein kinase type II subunit alpha/delta
Human_gene_id： 815/817
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=815
Human_swiss_prot_no： Q9UQM7/Q13557
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UQM7/entry
Mouse_gene_id： 12322/108058
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12322
Rat_gene_id： 25400/24246
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25400
Rat_swiss_prot_no： P11275/P15791
Rat_swiss_link： http://www.uniprot.org/uniprot/P11275
特异性： Phospho-CaMKIIα/δ (T286) Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein only when phosphorylated at T286.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2D; CAMKD; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II
实测条带： 54kD
信号通路： ErbB_HER;Calcium;Oocyte meiosis;WNT;WNT-T CELLLong-term potentiation;Neurotrophin;Olfactory transduction;GnRH;Melanogenesis;Glioma;
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Postsynaptic lipid rafts.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .
组织表达： Brain,
科研货号： PLP000041

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