HMGN1/2/3/4 (Acetyl Lys27/K33/K31) rabbit pAb

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商品货号： PLN000146

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： HMGN1 HMG14
蛋白名称： HMGN1/2/3/4 (Acetyl Lys27/K33/K31)
Human_gene_id： 3150
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3150
Human_swiss_prot_no： P05114/P05204/Q15651/O00479
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05114/entry
Mouse_gene_id： 100044391
Mouse_gene_link： https://www.uniprot.org/uniprot/100044391
Mouse_swiss_prot_no： P18608
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P18608
特异性： This antibody detects endogenous levels of Human,Mouse,Rat HMGN1/2/3/4 (Acetyl Lys27/K33/K31)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Non-histone chromosomal protein HMG-14 (High mobility group nucleosome-binding domain-containing protein 1)
实测条带： 12kD
功能： function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation on Ser-21 and Ser-25 weakens binding to nucleosomes and increases the rate of H3 phosphorylation (By similarity). Phosphorylation favors cytoplasmic localization.,RNA editing:Partially edited. A new initiator methionine may be created by a single uridine insertion in the 5'-UTR, causing an N-terminal extension of 45 amino acids. The existence of the RNA edited version is supported by direct protein sequencing by MS/MS of the following peptides specific to that version: 23-31 and 40-48. The RNA edited version is called ET-HMGN1.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.,
相关产品： RS0001,RS0002,YM3028,YM3186
细胞定位： Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.
科研货号： PLN000146

HMGN1/2/3/4 (Acetyl Lys27/K33/K31) rabbit pAb

Catalog No PLN000146

Product information

基因名称： HMGN1 HMG14
蛋白名称： HMGN1/2/3/4 (Acetyl Lys27/K33/K31)
Human_gene_id： 3150
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3150
Human_swiss_prot_no： P05114/P05204/Q15651/O00479
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05114/entry
Mouse_gene_id： 100044391
Mouse_gene_link： https://www.uniprot.org/uniprot/100044391
Mouse_swiss_prot_no： P18608
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P18608
特异性： This antibody detects endogenous levels of Human,Mouse,Rat HMGN1/2/3/4 (Acetyl Lys27/K33/K31)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Non-histone chromosomal protein HMG-14 (High mobility group nucleosome-binding domain-containing protein 1)
实测条带： 12kD
功能： function:Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2.,mass spectrometry: PubMed:10739259,PTM:Phosphorylation on Ser-21 and Ser-25 weakens binding to nucleosomes and increases the rate of H3 phosphorylation (By similarity). Phosphorylation favors cytoplasmic localization.,RNA editing:Partially edited. A new initiator methionine may be created by a single uridine insertion in the 5'-UTR, causing an N-terminal extension of 45 amino acids. The existence of the RNA edited version is supported by direct protein sequencing by MS/MS of the following peptides specific to that version: 23-31 and 40-48. The RNA edited version is called ET-HMGN1.,similarity:Belongs to the HMGN family.,subcellular location:Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.,
相关产品： RS0001,RS0002,YM3028,YM3186
细胞定位： Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.
科研货号： PLN000146

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