HMG-I/HMG-Y (Acetyl Lys71) rabbit pAb

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商品货号： PLN000143

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： HMGA1 HMGIY
蛋白名称： HMG-I/HMG-Y (Acetyl Lys71)
Human_gene_id： 3159
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3159
Human_swiss_prot_no： P17096
Human_swiss_link： https://www.uniprot.org/uniprotkb/P17096/entry
Mouse_gene_id： 111241
Mouse_gene_link： https://www.uniprot.org/uniprot/111241
Mouse_swiss_prot_no： P17095
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P17095
Rat_gene_id： 117062
Rat_gene_link： https://www.uniprot.org/uniprot/117062
Rat_swiss_prot_no： Q8K585
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q8K585
特异性： This antibody detects endogenous levels of Human, Mouse, Rat HMG-I/HMG-Y (Acetyl Lys71)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： High mobility group protein HMG-I/HMG-Y (HMG-I(Y);High mobility group AT-hook protein 1;High mobility group protein A1;High mobility group protein R)
实测条带： 12kD
功能： disease:A chromosomal aberration involving HMGA1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with RAD51L1.,function:HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.,mass spectrometry:With 1 acetyl and 2 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl and 3 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 1 methyl and 2 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 1 methyl and 3 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 2 methyl and 2 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 2 methyl and 3 phosphate groups PubMed:15302935,PTM:Constitutively phosphorylated on two or three sites. Phosphorylated upon DNA damage, probably by ATM or ATR. Hyperphosphorylated at early stages of apoptosis, followed by dephosphorylation and methylation, which coincides with chromatin condensation. Isoform HMG-Y can be phosphorylated by HIPK2.,PTM:HMG-Y is not methylated.,PTM:Methylation at Arg-58 is mutually exclusive with methylation at Arg-60.,similarity:Belongs to the HMGA family.,similarity:Contains 3 A.T hook DNA-binding domains.,subunit:Interacts with HIPK2 (By similarity). Interacts with HIV-1 pre-integration complex.,
相关产品： RS0001,RS0002,YM3028,YM3183
细胞定位： Nucleus. Chromosome.
科研货号： PLN000143

HMG-I/HMG-Y (Acetyl Lys71) rabbit pAb

Catalog No PLN000143

Product information

基因名称： HMGA1 HMGIY
蛋白名称： HMG-I/HMG-Y (Acetyl Lys71)
Human_gene_id： 3159
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3159
Human_swiss_prot_no： P17096
Human_swiss_link： https://www.uniprot.org/uniprotkb/P17096/entry
Mouse_gene_id： 111241
Mouse_gene_link： https://www.uniprot.org/uniprot/111241
Mouse_swiss_prot_no： P17095
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P17095
Rat_gene_id： 117062
Rat_gene_link： https://www.uniprot.org/uniprot/117062
Rat_swiss_prot_no： Q8K585
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q8K585
特异性： This antibody detects endogenous levels of Human, Mouse, Rat HMG-I/HMG-Y (Acetyl Lys71)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： High mobility group protein HMG-I/HMG-Y (HMG-I(Y);High mobility group AT-hook protein 1;High mobility group protein A1;High mobility group protein R)
实测条带： 12kD
功能： disease:A chromosomal aberration involving HMGA1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with RAD51L1.,function:HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.,mass spectrometry:With 1 acetyl and 2 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl and 3 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 1 methyl and 2 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 1 methyl and 3 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 2 methyl and 2 phosphate groups PubMed:15302935,mass spectrometry:With 1 acetyl, 2 methyl and 3 phosphate groups PubMed:15302935,PTM:Constitutively phosphorylated on two or three sites. Phosphorylated upon DNA damage, probably by ATM or ATR. Hyperphosphorylated at early stages of apoptosis, followed by dephosphorylation and methylation, which coincides with chromatin condensation. Isoform HMG-Y can be phosphorylated by HIPK2.,PTM:HMG-Y is not methylated.,PTM:Methylation at Arg-58 is mutually exclusive with methylation at Arg-60.,similarity:Belongs to the HMGA family.,similarity:Contains 3 A.T hook DNA-binding domains.,subunit:Interacts with HIPK2 (By similarity). Interacts with HIV-1 pre-integration complex.,
相关产品： RS0001,RS0002,YM3028,YM3183
细胞定位： Nucleus. Chromosome.
科研货号： PLN000143

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