Histone H2B (Acetyl Lys86) rabbit pAb

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商品货号： PLN000137

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： HIST1H2BB H2BFF
蛋白名称： Histone H2B (Acetyl Lys86)
Human_gene_id： 3018
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3018
Human_swiss_prot_no： P33778/P62807/P58876/Q93079/P06899/O60814/Q99880/Q99879/Q99877/P23527
Human_swiss_link： https://www.uniprot.org/uniprotkb/P33778/entry
Mouse_gene_id： 319178
Mouse_gene_link： https://www.uniprot.org/uniprot/319178
Mouse_swiss_prot_no： Q64475
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q64475
特异性： This antibody detects endogenous levels of Human,Mouse,Rat Histone H2B (Acetyl Lys86)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Histone H2B type 1-B (Histone H2B.1;Histone H2B.f;H2B/f)
实测条带： 14kD
功能： function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Monoubiquitination of Lys-121 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.,PTM:Phosphorylated on Ser-15 by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.,similarity:Belongs to the histone H2B family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,
相关产品： RS0001,RS0002,YM3028,YM3177
细胞定位： Nucleus. Chromosome.
科研货号： PLN000137

Histone H2B (Acetyl Lys86) rabbit pAb

Catalog No PLN000137

Product information

基因名称： HIST1H2BB H2BFF
蛋白名称： Histone H2B (Acetyl Lys86)
Human_gene_id： 3018
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3018
Human_swiss_prot_no： P33778/P62807/P58876/Q93079/P06899/O60814/Q99880/Q99879/Q99877/P23527
Human_swiss_link： https://www.uniprot.org/uniprotkb/P33778/entry
Mouse_gene_id： 319178
Mouse_gene_link： https://www.uniprot.org/uniprot/319178
Mouse_swiss_prot_no： Q64475
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q64475
特异性： This antibody detects endogenous levels of Human,Mouse,Rat Histone H2B (Acetyl Lys86)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Histone H2B type 1-B (Histone H2B.1;Histone H2B.f;H2B/f)
实测条带： 14kD
功能： function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Monoubiquitination of Lys-121 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.,PTM:Phosphorylated on Ser-15 by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.,similarity:Belongs to the histone H2B family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,
相关产品： RS0001,RS0002,YM3028,YM3177
细胞定位： Nucleus. Chromosome.
科研货号： PLN000137

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