Topoisomerase IIα (ABT272) Mouse mAb

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商品货号： PLD000238

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： TOP2A TOP2
蛋白名称： Topoisomerase IIα
Human_gene_id： 7153
Human_gene_link： https://www.ncbi.nlm.nih.gov/gene/?term=TOP2A
Human_swiss_prot_no： P11388
Human_swiss_link： https://www.uniprot.org/uniprotkb/P11388/entry
特异性： The antibody can specifically recognize human Topoisomerase IIα protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： IHC-p 1:200-400, WB 1:200-1000
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： YM6914.pdf
Msds： MSDS_Antibody.pdf
其他名称： DNA topoisomerase 2-alpha (EC 5.99.1.3;DNA topoisomerase II, alpha isozyme)
功能： catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA.,enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.,function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.,miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.,PTM:Phosphorylation has no effect on catalytic activity.,similarity:Belongs to the type II topoisomerase family.,subcellular location:Generally located in the nucleoplasm.,subunit:Homodimer. Interacts with COPS5.,
相关产品： YM6594R,YT5049,YT4702,YT4701,YT4700,YT4699,YP0836,YP0759,YP0446,YM6594,YM6515,KA3536C,KA1764C,KA1729C,KA1510C
细胞定位： Cytoplasm . Nucleus, nucleoplasm . Nucleus . Nucleus, nucleolus .
组织表达： Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung (PubMed:9155056). Also found in high-grade lymphomas, squamous cell lung tumors and seminomas (PubMed:9155056).
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科研货号： PLD000238

Topoisomerase IIα (ABT272) Mouse mAb

Catalog No PLD000238

Product information

基因名称： TOP2A TOP2
蛋白名称： Topoisomerase IIα
Human_gene_id： 7153
Human_gene_link： https://www.ncbi.nlm.nih.gov/gene/?term=TOP2A
Human_swiss_prot_no： P11388
Human_swiss_link： https://www.uniprot.org/uniprotkb/P11388/entry
特异性： The antibody can specifically recognize human Topoisomerase IIα protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： IHC-p 1:200-400, WB 1:200-1000
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： YM6914.pdf
Msds： MSDS_Antibody.pdf
其他名称： DNA topoisomerase 2-alpha (EC 5.99.1.3;DNA topoisomerase II, alpha isozyme)
功能： catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA.,enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.,function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.,miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.,PTM:Phosphorylation has no effect on catalytic activity.,similarity:Belongs to the type II topoisomerase family.,subcellular location:Generally located in the nucleoplasm.,subunit:Homodimer. Interacts with COPS5.,
相关产品： YM6594R,YT5049,YT4702,YT4701,YT4700,YT4699,YP0836,YP0759,YP0446,YM6594,YM6515,KA3536C,KA1764C,KA1729C,KA1510C
细胞定位： Cytoplasm . Nucleus, nucleoplasm . Nucleus . Nucleus, nucleolus .
组织表达： Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung (PubMed:9155056). Also found in high-grade lymphomas, squamous cell lung tumors and seminomas (PubMed:9155056).
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科研货号： PLD000238

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