Thyroid Peroxidase(TPO) rabbit mAb(ABT45R)

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商品货号： PLD000161

适应性： 人

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： TPO
蛋白名称： Thyroid Peroxidase(TPO)
Human_gene_id： 3662
Human_gene_link： https://www.ncbi.nlm.nih.gov/gene/?term=TPO
Human_swiss_prot_no： P07202
Human_swiss_link： https://www.uniprot.org/uniprotkb/P07202/entry
特异性： This antibody detects endogenous levels of Thyroid Peroxidase(TPO) at Human
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p 1:200. IF 1:50-200
纯化工艺： The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Thyroid peroxidase (TPO;EC 1.11.1.8)
功能： alternative products:Additional isoforms seem to exist,catalytic activity:2 iodide + H(2)O(2) + 2 H(+) = 2 iodine + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:An alternative splicing in the thyroperoxidase mRNA can cause Graves' disease.,disease:Defects in TPO are the cause of congenital hypothyroidism due to dyshormonogenesis type 2A (CHDH2A) [MIM:274500]; also called genetic defect in thyroid hormonogenesis 2A or thyroid hormone organification defect II. CHDH2A is due to defective conversion of accumulated iodide to organically bound iodine. The iodide organification defect can be partial or complete.,function:Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).,online information:Thyroid peroxidase entry,pathway:Hormone biosynthesis; thyroid hormone biosynthesis.,PTM:Cleaved in its N-terminal part.,PTM:Glycosylated.,PTM:Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface.,similarity:Belongs to the peroxidase family. XPO subfamily.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,subunit:Interacts with DUOX1, DUOX2 and CYBA.,
相关产品： YM6102R,RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface.
组织表达： Glandular pool- thyroid,Spleen,Thyroid,
科研货号： PLD000161

Thyroid Peroxidase(TPO) rabbit mAb(ABT45R)

Catalog No PLD000161

Product information

基因名称： TPO
蛋白名称： Thyroid Peroxidase(TPO)
Human_gene_id： 3662
Human_gene_link： https://www.ncbi.nlm.nih.gov/gene/?term=TPO
Human_swiss_prot_no： P07202
Human_swiss_link： https://www.uniprot.org/uniprotkb/P07202/entry
特异性： This antibody detects endogenous levels of Thyroid Peroxidase(TPO) at Human
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p 1:200. IF 1:50-200
纯化工艺： The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Thyroid peroxidase (TPO;EC 1.11.1.8)
功能： alternative products:Additional isoforms seem to exist,catalytic activity:2 iodide + H(2)O(2) + 2 H(+) = 2 iodine + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:An alternative splicing in the thyroperoxidase mRNA can cause Graves' disease.,disease:Defects in TPO are the cause of congenital hypothyroidism due to dyshormonogenesis type 2A (CHDH2A) [MIM:274500]; also called genetic defect in thyroid hormonogenesis 2A or thyroid hormone organification defect II. CHDH2A is due to defective conversion of accumulated iodide to organically bound iodine. The iodide organification defect can be partial or complete.,function:Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).,online information:Thyroid peroxidase entry,pathway:Hormone biosynthesis; thyroid hormone biosynthesis.,PTM:Cleaved in its N-terminal part.,PTM:Glycosylated.,PTM:Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface.,similarity:Belongs to the peroxidase family. XPO subfamily.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,subunit:Interacts with DUOX1, DUOX2 and CYBA.,
相关产品： YM6102R,RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface.
组织表达： Glandular pool- thyroid,Spleen,Thyroid,
科研货号： PLD000161

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