特异性: This antibody detects endogenous levels of human Mesothelin . Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Mouse, Monoclonal/IgG2b, Kappa
稀释: IHC-p 1:50-300, WB 1:500-2000
纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
功能: disease:Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.,function:Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.,function:Membrane-anchored forms may play a role in cellular adhesion.,PTM:Both MPF and the cleaved form of mesothelin are N-glycosylated.,PTM:Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.,similarity:Belongs to the mesothelin family.,subunit:Interacts with MUC16.,tissue specificity:Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).,
组织表达: Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
特异性: This antibody detects endogenous levels of human Mesothelin . Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Mouse, Monoclonal/IgG2b, Kappa
稀释: IHC-p 1:50-300, WB 1:500-2000
纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
功能: disease:Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.,function:Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.,function:Membrane-anchored forms may play a role in cellular adhesion.,PTM:Both MPF and the cleaved form of mesothelin are N-glycosylated.,PTM:Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.,similarity:Belongs to the mesothelin family.,subunit:Interacts with MUC16.,tissue specificity:Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).,
组织表达: Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).