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Proliferating Cell Nuclear Antigen (ABT221) Mouse mAb
商品货号: PLD000131
适 应 性: 人,小鼠,大鼠
WB IHC ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: PCNA
  • 蛋白名称: ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;etID36690.10;fa28e03;fb36g03;HGCN8729;MGC8367;Mutagen-sensitive 209 protein;OTTHUMP00000030189;OTTHUMP00000030190;PCNA;Pcna/cyclin;PCNA_HUMAN;PCNAR;Polymerase delta accessory protein;Proliferating cell nuclear antigen;wu:fa28e03;wu:fb36g03
  • Human_swiss_prot_no: P12004
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P12004/entry
  • Mouse_swiss_prot_no: P17918
  • Rat_swiss_prot_no: P04961
  • 特异性: The antibody can specifically recognize human PCNA protein. In western blotting of Hela, A431 and HEK293 cell lysates, the antibody can label a 30 kDa band corresponding to PCNA.
  • 组成: PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
  • 来源: Monoclonal Mouse IgG2b, kappa
  • 稀释: IHC-p 1:200-400,WB 500-1000
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: YM6705.pdf
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;etID36690.10;fa28e03;fb36g03;HGCN8729;MGC8367;Mutagen-sensitive 209 protein;OTTHUMP00000030189;OTTHUMP00000030190;PCNA;Pcna/cyclin;PCNA_HUMAN;PCNAR;Polymerase delta accessory protein;Proliferating cell nuclear antigen;wu:fa28e03;wu:fb36g03
  • 分子量: 29kD
  • 功能: disease:Antibodies are present in sera from patients with systemic lupus erythematosus.,function:This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.,online information:PCNA entry,PTM:Upon methyl methanesulfonate-induced DNA damage, mono-ubiquitinated by the UBE2B-RAD18 complex on Lys-164. This induces non-canonical poly-ubiquitination on Lys-164 through 'Lys-63' linkage of ubiquitin moieties by the E2 complex UBE2N-UBE2V2 and the E3 ligases RNF8 and SHPRH, which are required for DNA repair.,similarity:Belongs to the PCNA family.,subunit:Homotrimer. Interacts with KCTD10. Interacts with PPP1R15A (By similarity). Forms a complex with activator 1 heteropentamer in the presence of ATP. Interacts with POLH, POLK, DNMT1, ERCC5/XPG, FEN1, CDC6, APEX2 and POLDIP2. Interacts with EXO1 and SHPRH. Forms a ternary complex with DNTTIP2 and core histone. Interacts with POLD1, POLD3 and POLD4. Interacts with BAZ1B/WSTF; the interaction is direct.,
  • 相关产品: YT6075,YT3617,YM6211,YM6090,YM3031,YM2139,YM2138,YM2137,YM2136,YM2135,YM2134,YM2133,YM2132,YM2131,YM2130,YM2129,YM2128,KA3356C
  • 细胞定位: Nuclear
  • 组织表达: Tonsil/ Colon
  • tag: hot
  • 科研货号: PLD000131
Proliferating Cell Nuclear Antigen (ABT221) Mouse mAb
Catalog No PLD000131
Product information
  • 基因名称: PCNA
  • 蛋白名称: ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;etID36690.10;fa28e03;fb36g03;HGCN8729;MGC8367;Mutagen-sensitive 209 protein;OTTHUMP00000030189;OTTHUMP00000030190;PCNA;Pcna/cyclin;PCNA_HUMAN;PCNAR;Polymerase delta accessory protein;Proliferating cell nuclear antigen;wu:fa28e03;wu:fb36g03
  • Human_swiss_prot_no: P12004
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P12004/entry
  • Mouse_swiss_prot_no: P17918
  • Rat_swiss_prot_no: P04961
  • 特异性: The antibody can specifically recognize human PCNA protein. In western blotting of Hela, A431 and HEK293 cell lysates, the antibody can label a 30 kDa band corresponding to PCNA.
  • 组成: PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
  • 来源: Monoclonal Mouse IgG2b, kappa
  • 稀释: IHC-p 1:200-400,WB 500-1000
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: YM6705.pdf
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;etID36690.10;fa28e03;fb36g03;HGCN8729;MGC8367;Mutagen-sensitive 209 protein;OTTHUMP00000030189;OTTHUMP00000030190;PCNA;Pcna/cyclin;PCNA_HUMAN;PCNAR;Polymerase delta accessory protein;Proliferating cell nuclear antigen;wu:fa28e03;wu:fb36g03
  • 分子量: 29kD
  • 功能: disease:Antibodies are present in sera from patients with systemic lupus erythematosus.,function:This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.,online information:PCNA entry,PTM:Upon methyl methanesulfonate-induced DNA damage, mono-ubiquitinated by the UBE2B-RAD18 complex on Lys-164. This induces non-canonical poly-ubiquitination on Lys-164 through 'Lys-63' linkage of ubiquitin moieties by the E2 complex UBE2N-UBE2V2 and the E3 ligases RNF8 and SHPRH, which are required for DNA repair.,similarity:Belongs to the PCNA family.,subunit:Homotrimer. Interacts with KCTD10. Interacts with PPP1R15A (By similarity). Forms a complex with activator 1 heteropentamer in the presence of ATP. Interacts with POLH, POLK, DNMT1, ERCC5/XPG, FEN1, CDC6, APEX2 and POLDIP2. Interacts with EXO1 and SHPRH. Forms a ternary complex with DNTTIP2 and core histone. Interacts with POLD1, POLD3 and POLD4. Interacts with BAZ1B/WSTF; the interaction is direct.,
  • 相关产品: YT6075,YT3617,YM6211,YM6090,YM3031,YM2139,YM2138,YM2137,YM2136,YM2135,YM2134,YM2133,YM2132,YM2131,YM2130,YM2129,YM2128,KA3356C
  • 细胞定位: Nuclear
  • 组织表达: Tonsil/ Colon
  • tag: hot
  • 科研货号: PLD000131
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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