特异性： This antibody detects endogenous levels of human Tissue Inhibitor of Metalloproteinases 1(TIMP1). Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： WB 1:20-50
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
功能： function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.,PTM:The activity of TIMP1 is dependent on the presence of disulfide bonds.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,
相关产品： YM6673R,YT4658,YM6673,KE1064,KA3397C
细胞定位： Secreted .
组织表达： Detected in rheumatoid synovial fluid (at protein level).
科研货号： PLD000123
TIMP1 (ABT-TIMP1) Mouse mAb
Catalog NoPLD000123
Product information
基因名称： TIMP1 CLGI TIMP
蛋白名称： Tissue Inhibitor of Metalloproteinases 1(TIMP1)
特异性： This antibody detects endogenous levels of human Tissue Inhibitor of Metalloproteinases 1(TIMP1). Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： WB 1:20-50
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
功能： function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.,PTM:The activity of TIMP1 is dependent on the presence of disulfide bonds.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,
相关产品： YM6673R,YT4658,YM6673,KE1064,KA3397C
细胞定位： Secreted .
组织表达： Detected in rheumatoid synovial fluid (at protein level).
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