特异性: This antibody detects endogenous levels of human Claudin 3. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section. The antibody was also Predict react with Mouse;Rat
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Mouse, Monoclonal/IgG1, Kappa
稀释: IHC-p 1:200-400,WB 1:500-2000.
纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
功能: disease:Haploinsufficiency of CLDN3 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
特异性: This antibody detects endogenous levels of human Claudin 3. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section. The antibody was also Predict react with Mouse;Rat
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Mouse, Monoclonal/IgG1, Kappa
稀释: IHC-p 1:200-400,WB 1:500-2000.
纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
功能: disease:Haploinsufficiency of CLDN3 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,