特异性： This antibody detects endogenous levels of human Cytokeratin 13. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： IHC-p 1:200-400,WB 1:500-2000
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
功能： disease:Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,online information:Keratin-13 entry,PTM:O-glycosylated; glycans consist of single N-acetylglucosamine residues.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.,tissue specificity:Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasmic, Membranous
组织表达： Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
科研货号： PLD000058
Cytokeratin 13 (ABT-CK13) mouse mAb
Catalog NoPLD000058
Product information
基因名称： KRT13
蛋白名称： Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)
特异性： This antibody detects endogenous levels of human Cytokeratin 13. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： IHC-p 1:200-400,WB 1:500-2000
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
功能： disease:Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,online information:Keratin-13 entry,PTM:O-glycosylated; glycans consist of single N-acetylglucosamine residues.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.,tissue specificity:Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasmic, Membranous
组织表达： Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
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