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Uroplakin III (ABT-UPK3) mouse mAb
商品货号: PLD000048
适 应 性: 人,小鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: UPK3A UPK3
  • 蛋白名称: Uroplakin-3a (UP3a) (Uroplakin III) (UPIII)
  • Human_gene_id: 7380
  • Human_swiss_prot_no: O75631
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/O75631/entry
  • 特异性: This antibody detects endogenous levels of human Uroplakin III. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Mouse, Monoclonal/IgG1, Lambda
  • 稀释: WB 1:500-2000, IHC-p 1:200-400, IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: YM6138.pdf
  • Msds: MSDS_Antibody.pdf
  • 功能: disease:Defects in UPK3A are a cause of renal adysplasia [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.,function:Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.,similarity:Belongs to the uroplakin-3 family.,subcellular location:Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).,subunit:Heterodimer with uroplakin-1B (UPK1B).,tissue specificity:Expressed in ureter.,
  • 相关产品: YM6138R,YN2450,YM6138,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). .
  • 组织表达: Expressed in ureter.
  • 科研货号: PLD000048
Uroplakin III (ABT-UPK3) mouse mAb
Catalog No PLD000048
Product information
  • 基因名称: UPK3A UPK3
  • 蛋白名称: Uroplakin-3a (UP3a) (Uroplakin III) (UPIII)
  • Human_gene_id: 7380
  • Human_swiss_prot_no: O75631
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/O75631/entry
  • 特异性: This antibody detects endogenous levels of human Uroplakin III. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Mouse, Monoclonal/IgG1, Lambda
  • 稀释: WB 1:500-2000, IHC-p 1:200-400, IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: YM6138.pdf
  • Msds: MSDS_Antibody.pdf
  • 功能: disease:Defects in UPK3A are a cause of renal adysplasia [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.,function:Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.,similarity:Belongs to the uroplakin-3 family.,subcellular location:Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).,subunit:Heterodimer with uroplakin-1B (UPK1B).,tissue specificity:Expressed in ureter.,
  • 相关产品: YM6138R,YN2450,YM6138,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). .
  • 组织表达: Expressed in ureter.
  • 科研货号: PLD000048
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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