特异性： This antibody detects endogenous levels of human MUC2. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG2b, Kappa
稀释： IHC-p 1:200-400
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
功能： function:Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.,polymorphism:The number of repeats is highly polymorphic and varies among different alleles.,PTM:At low pH of 6 and under, undergoes autocatalytic cleavage in vitro in the N-terminal region of the fourth VWD domain. It is likely that this also occurs in vivo and is triggered by the low pH of the late secretory pathway.,PTM:May undergo proteolytic cleavage in the outer mucus layer of the colon, contributing to the expanded volume and loose nature of this layer which allows for bacterial colonization in contrast to the inner mucus layer which is dense and devoid of bacteria.,PTM:O-glycosylated.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 TIL (trypsin inhibitory-like) domain.,similarity:Contains 2 VWFC domains.,similarity:Contains 4 VWFD domains.,subunit:Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with FCGBP.,tissue specificity:Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted. In the intestine, secreted into the inner and outer mucus layers. .
组织表达： Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
特异性： This antibody detects endogenous levels of human MUC2. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Mouse, Monoclonal/IgG2b, Kappa
稀释： IHC-p 1:200-400
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
功能： function:Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.,polymorphism:The number of repeats is highly polymorphic and varies among different alleles.,PTM:At low pH of 6 and under, undergoes autocatalytic cleavage in vitro in the N-terminal region of the fourth VWD domain. It is likely that this also occurs in vivo and is triggered by the low pH of the late secretory pathway.,PTM:May undergo proteolytic cleavage in the outer mucus layer of the colon, contributing to the expanded volume and loose nature of this layer which allows for bacterial colonization in contrast to the inner mucus layer which is dense and devoid of bacteria.,PTM:O-glycosylated.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 TIL (trypsin inhibitory-like) domain.,similarity:Contains 2 VWFC domains.,similarity:Contains 4 VWFD domains.,subunit:Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with FCGBP.,tissue specificity:Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted. In the intestine, secreted into the inner and outer mucus layers. .
组织表达： Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
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