蛋白名称： CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
特异性： The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the antibody can label a 51 kDa band corresponding to CK7 in A549 and Hela cell lysates.
组成： PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： IHC-p 1:200-400,WB 500-1000
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
其他名称： CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
分子量： 52kD
功能： function:Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).,induction:Up-regulated by retinoic acid.,mass spectrometry: PubMed:11840567,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Arg-20 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit EIF3S10 and with HPV16 E7.,tissue specificity:Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasmic, Membranous
组织表达： Pancreas
科研货号： PLD000012
Cytokeratin 7 (ABT436) Mouse mAb
Catalog NoPLD000012
Product information
基因名称： KRT7 SCL
蛋白名称： CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
特异性： The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the antibody can label a 51 kDa band corresponding to CK7 in A549 and Hela cell lysates.
组成： PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
来源： Mouse, Monoclonal/IgG1, Kappa
稀释： IHC-p 1:200-400,WB 500-1000
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
其他名称： CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
分子量： 52kD
功能： function:Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).,induction:Up-regulated by retinoic acid.,mass spectrometry: PubMed:11840567,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Arg-20 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit EIF3S10 and with HPV16 E7.,tissue specificity:Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.,
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