细胞定位： Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated in the cytoplasm and nucleus.
组织表达： In colorectal cancer tissue, expression is highest in the surface epithelium of normal colonic mucosa adjacent to the cancer tissue but is largely excluded from the crypt bases. Expression is lost or significantly decreased in 80% of tested tumors (at protein level).
细胞定位： Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated in the cytoplasm and nucleus.
组织表达： In colorectal cancer tissue, expression is highest in the surface epithelium of normal colonic mucosa adjacent to the cancer tissue but is largely excluded from the crypt bases. Expression is lost or significantly decreased in 80% of tested tumors (at protein level).
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