其他名称： G protein-activated inward rectifier potassium channel 2 (GIRK-2;BIR1;Inward rectifier K(+) channel Kir3.2;KATP-2;Potassium channel, inwardly rectifying subfamily J member 6)
实测条带： 48kD
功能： function:This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.,similarity:Belongs to the inward rectifier-type potassium channel family.,subunit:Associates with GIRK1 or GIRK4 to form a G-protein-activated heteromultimer pore-forming unit. The resulting inward current is much larger.,tissue specificity:Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Multi-pass membrane protein.
组织表达： Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
其他名称： G protein-activated inward rectifier potassium channel 2 (GIRK-2;BIR1;Inward rectifier K(+) channel Kir3.2;KATP-2;Potassium channel, inwardly rectifying subfamily J member 6)
实测条带： 48kD
功能： function:This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.,similarity:Belongs to the inward rectifier-type potassium channel family.,subunit:Associates with GIRK1 or GIRK4 to form a G-protein-activated heteromultimer pore-forming unit. The resulting inward current is much larger.,tissue specificity:Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Multi-pass membrane protein.
组织表达： Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas.
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