功能： disease:Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).,function:Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Angiotensin receptor entry,online information:The Singapore human mutation and polymorphism database,PTM:C-terminal Ser or Thr residues may be phosphorylated.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Liver, lung, adrenal and adrenocortical adenomas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein .
组织表达： Liver, lung, adrenal and adrenocortical adenomas.
科研货号： PLA019677
AGTR1 Polyclonal Antibody
Catalog NoPLA019677
Product information
基因名称： AGTR1 AGTR1A AGTR1B AT2R1 AT2R1B
蛋白名称： Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)
功能： disease:Defects in AGTR1 are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).,function:Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Angiotensin receptor entry,online information:The Singapore human mutation and polymorphism database,PTM:C-terminal Ser or Thr residues may be phosphorylated.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Liver, lung, adrenal and adrenocortical adenomas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Multi-pass membrane protein .
组织表达： Liver, lung, adrenal and adrenocortical adenomas.
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