Granzyme B Polyclonal Antibody

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商品货号： PLA019662

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： GZMB CGL1 CSPB CTLA1 GRB
蛋白名称： Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)
Human_gene_id： 3002
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3002
Human_swiss_prot_no： P10144
Human_swiss_link： http://www.uniprot.org/uniprotkb/P10144/entry
Mouse_gene_id： 14939
Mouse_swiss_prot_no： P04187
Mouse_swiss_link： http://www.uniprot.org/uniprot/P04187
Rat_gene_id： 100361468
Rat_swiss_prot_no： P18291
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P18291
特异性： This antibody detects endogenous levels of Granzyme B.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Granzyme B (EC 3.4.21.79;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E)
实测条带： 38kD
信号通路： Natural killer cell mediated cytotoxicity;Type I diabetes mellitus;Autoimmune thyroid disease;Allograft rejection;Graft-versus-host disease;
功能： catalytic activity:Preferential cleavage: -Asp-|-Xaa- >> -Asn-|-Xaa- > -Met-|-Xaa-, -Ser-|-Xaa-.,function:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.,induction:By staphylococcal enterotoxin A (SEA) in peripheral blood leukocytes.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,subcellular location:Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted . Cytolytic granule . Delivered into the target cell by perforin (PubMed:20038786). .
组织表达： Breast carcinoma,Large granular lymphocyte leukemia,Pancreas,
科研货号： PLA019662

Granzyme B Polyclonal Antibody

Catalog No PLA019662

Product information

基因名称： GZMB CGL1 CSPB CTLA1 GRB
蛋白名称： Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)
Human_gene_id： 3002
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3002
Human_swiss_prot_no： P10144
Human_swiss_link： http://www.uniprot.org/uniprotkb/P10144/entry
Mouse_gene_id： 14939
Mouse_swiss_prot_no： P04187
Mouse_swiss_link： http://www.uniprot.org/uniprot/P04187
Rat_gene_id： 100361468
Rat_swiss_prot_no： P18291
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P18291
特异性： This antibody detects endogenous levels of Granzyme B.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Granzyme B (EC 3.4.21.79;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E)
实测条带： 38kD
信号通路： Natural killer cell mediated cytotoxicity;Type I diabetes mellitus;Autoimmune thyroid disease;Allograft rejection;Graft-versus-host disease;
功能： catalytic activity:Preferential cleavage: -Asp-|-Xaa- >> -Asn-|-Xaa- > -Met-|-Xaa-, -Ser-|-Xaa-.,function:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.,induction:By staphylococcal enterotoxin A (SEA) in peripheral blood leukocytes.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,subcellular location:Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted . Cytolytic granule . Delivered into the target cell by perforin (PubMed:20038786). .
组织表达： Breast carcinoma,Large granular lymphocyte leukemia,Pancreas,
科研货号： PLA019662

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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