功能: disease:Defects in AVPR2 are the cause of diabetes insipidus nephrogenic X-linked (XNDI) [MIM:304800]; also known as diabetes insipidus nephrogenic type 1. XNDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia.,disease:Defects in AVPR2 are the cause of nephrogenic syndrome of inappropriate antidiuresis (NSIAD) [MIM:300539]. This disorder is characterized by an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolarity, and natriuresis.,function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.,online information:AVPR2 pages,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Multi-pass membrane protein .
功能: disease:Defects in AVPR2 are the cause of diabetes insipidus nephrogenic X-linked (XNDI) [MIM:304800]; also known as diabetes insipidus nephrogenic type 1. XNDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia.,disease:Defects in AVPR2 are the cause of nephrogenic syndrome of inappropriate antidiuresis (NSIAD) [MIM:300539]. This disorder is characterized by an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolarity, and natriuresis.,function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.,online information:AVPR2 pages,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Multi-pass membrane protein .