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Thioredoxin Polyclonal Antibody
商品货号: PLA019613
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: TXN TRDX TRX TRX1
  • 蛋白名称: Thioredoxin
  • Human_gene_id: 7295
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7295
  • Human_swiss_prot_no: P10599
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P10599/entry
  • Mouse_gene_id: 22166
  • Mouse_swiss_prot_no: P10639
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P10639
  • 特异性: This antibody detects endogenous levels of Thioredoxin
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Thioredoxin (Trx;ATL-derived factor;ADF;Surface-associated sulphydryl protein;SASP)
  • 实测条带: 12kD
  • 功能: function:ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).,function:Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.,PTM:In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3.,
  • 相关产品: YT6065,YM0618,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). .
  • 组织表达: Brain,Cajal-Retzius cell,Cerebellum,Cervix,Epithelium,Fetal brain cortex,Hepatocyte,Lens,Ma
  • 科研货号: PLA019613
Thioredoxin Polyclonal Antibody
Catalog No PLA019613
Product information
  • 基因名称: TXN TRDX TRX TRX1
  • 蛋白名称: Thioredoxin
  • Human_gene_id: 7295
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7295
  • Human_swiss_prot_no: P10599
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P10599/entry
  • Mouse_gene_id: 22166
  • Mouse_swiss_prot_no: P10639
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P10639
  • 特异性: This antibody detects endogenous levels of Thioredoxin
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Thioredoxin (Trx;ATL-derived factor;ADF;Surface-associated sulphydryl protein;SASP)
  • 实测条带: 12kD
  • 功能: function:ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).,function:Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.,PTM:In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3.,
  • 相关产品: YT6065,YM0618,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). .
  • 组织表达: Brain,Cajal-Retzius cell,Cerebellum,Cervix,Epithelium,Fetal brain cortex,Hepatocyte,Lens,Ma
  • 科研货号: PLA019613
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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