其他名称: Bone morphogenetic protein 1 (BMP-1;EC 3.4.24.19;Mammalian tolloid protein;mTld;Procollagen C-proteinase;PCP)
功能: catalytic activity:Cleavage of the C-terminal propeptide at Ala-|-Asp in type I and II procollagens and at Arg-|-Asp in type III.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Activity is increased by the procollagen C-endopeptidase enhancer protein.,function:Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD).,similarity:Belongs to the peptidase M12A family.,similarity:Contains 2 EGF-like domains.,similarity:Contains 5 CUB domains.,tissue specificity:Ubiquitous.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Golgi apparatus, trans-Golgi network . Secreted, extracellular space, extracellular matrix . Secreted . Co-localizes with POSTN in the Golgi. .; [Isoform BMP1-3]: Secreted .
组织表达: Ubiquitous.
科研货号: PLA019538
BMP-1 Polyclonal Antibody
Catalog NoPLA019538
Product information
基因名称: BMP1 PCOLC
蛋白名称: Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
其他名称: Bone morphogenetic protein 1 (BMP-1;EC 3.4.24.19;Mammalian tolloid protein;mTld;Procollagen C-proteinase;PCP)
功能: catalytic activity:Cleavage of the C-terminal propeptide at Ala-|-Asp in type I and II procollagens and at Arg-|-Asp in type III.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Activity is increased by the procollagen C-endopeptidase enhancer protein.,function:Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD).,similarity:Belongs to the peptidase M12A family.,similarity:Contains 2 EGF-like domains.,similarity:Contains 5 CUB domains.,tissue specificity:Ubiquitous.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Golgi apparatus, trans-Golgi network . Secreted, extracellular space, extracellular matrix . Secreted . Co-localizes with POSTN in the Golgi. .; [Isoform BMP1-3]: Secreted .