其他名称： Hepatoma-derived growth factor (HDGF;High mobility group protein 1-like 2;HMG-1L2)
功能： domain:The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.,function:Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.,PTM:Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.,similarity:Belongs to the HDGF family.,similarity:Contains 1 PWWP domain.,subunit:Monomer, and domain-swapped homodimer.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477). .; [Isoform 2]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .; [Isoform 3]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .
组织表达： Ubiquitous.
科研货号： PLA019535
HDGF Polyclonal Antibody
Catalog NoPLA019535
Product information
基因名称： HDGF HMG1L2
蛋白名称： Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
其他名称： Hepatoma-derived growth factor (HDGF;High mobility group protein 1-like 2;HMG-1L2)
功能： domain:The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.,function:Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.,PTM:Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.,similarity:Belongs to the HDGF family.,similarity:Contains 1 PWWP domain.,subunit:Monomer, and domain-swapped homodimer.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477). .; [Isoform 2]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .; [Isoform 3]: Nucleus . Cytoplasm . Secreted, extracellular exosome . Secreted by exosomes and is located on the outer exosome surface. .
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