信号通路： MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Cytokine-cytokine receptor interaction;Endocytosis;Focal adhesion;Gap junction;Regulates Actin and Cytoskeleton;Pathways in cancer;Pancreatic cancer;Endometrial cancer;Glioma;Prostate cancer;Melanoma;Bladder cancer;Non-small cell lung cancer;
功能： disease:Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.,function:EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.,online information:Epidermal growth factor entry,similarity:Contains 9 EGF-like domains.,similarity:Contains 9 LDL-receptor class B repeats.,tissue specificity:Expressed in kidney, salivary gland, cerebrum and prostate.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Single-pass type I membrane protein.
组织表达： Expressed in kidney, salivary gland, cerebrum and prostate.
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Cytokine-cytokine receptor interaction;Endocytosis;Focal adhesion;Gap junction;Regulates Actin and Cytoskeleton;Pathways in cancer;Pancreatic cancer;Endometrial cancer;Glioma;Prostate cancer;Melanoma;Bladder cancer;Non-small cell lung cancer;
功能： disease:Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4) [MIM:611718]; also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes.,function:EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.,online information:Epidermal growth factor entry,similarity:Contains 9 EGF-like domains.,similarity:Contains 9 LDL-receptor class B repeats.,tissue specificity:Expressed in kidney, salivary gland, cerebrum and prostate.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Single-pass type I membrane protein.
组织表达： Expressed in kidney, salivary gland, cerebrum and prostate.
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