功能: function:Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.,online information:Bone morphogenetic protein 10 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted .
组织表达: Detected in mammary epithelia (at protein level).
功能: function:Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.,online information:Bone morphogenetic protein 10 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted .
组织表达: Detected in mammary epithelia (at protein level).