信号通路： MAPK_ERK_Growth;MAPK_G_Protein;Endocytosis;Regulates Actin and Cytoskeleton;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.,PTM:Glycosylated (By similarity). Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Isoform 2 may be secreted.,subunit:Interacts with KLB.,tissue specificity:Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum. Internalized from the cell membrane to recycling endosomes, and from there back to the cell membrane.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm .
组织表达： Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;Endocytosis;Regulates Actin and Cytoskeleton;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.,PTM:Glycosylated (By similarity). Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Isoform 2 may be secreted.,subunit:Interacts with KLB.,tissue specificity:Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum. Internalized from the cell membrane to recycling endosomes, and from there back to the cell membrane.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm .
组织表达： Expressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.
在线咨询
湘公网安备