功能: catalytic activity:N-acylsphingosine + H(2)O = a carboxylate + sphingosine.,enzyme regulation:Inhibited by sphingosine.,function:Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.,similarity:Belongs to the alkaline ceramidase family.,tissue specificity:Mainly expressed in epidermis.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能: catalytic activity:N-acylsphingosine + H(2)O = a carboxylate + sphingosine.,enzyme regulation:Inhibited by sphingosine.,function:Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.,similarity:Belongs to the alkaline ceramidase family.,tissue specificity:Mainly expressed in epidermis.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Endoplasmic reticulum membrane ; Multi-pass membrane protein .