其他名称: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
实测条带: 115kD
信号通路: Homologous recombination;
功能: catalytic activity:ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.,function:Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.,similarity:Belongs to the prokaryotic type I/III topoisomerase family.,subunit:Directly interacts with BLM and RMI1. Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.,tissue specificity:High expression is found in testis, heart, skeletal muscle and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Mitochondrion matrix .
组织表达: High expression is found in testis, heart, skeletal muscle and pancreas.
其他名称: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
实测条带: 115kD
信号通路: Homologous recombination;
功能: catalytic activity:ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.,function:Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.,similarity:Belongs to the prokaryotic type I/III topoisomerase family.,subunit:Directly interacts with BLM and RMI1. Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.,tissue specificity:High expression is found in testis, heart, skeletal muscle and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Mitochondrion matrix .
组织表达: High expression is found in testis, heart, skeletal muscle and pancreas.