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Topo IIIα Polyclonal Antibody
商品货号: PLA019294
适 应 性: 人,小鼠
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: TOP3A
  • 蛋白名称: DNA topoisomerase 3-alpha
  • Human_gene_id: 7156
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7156
  • Human_swiss_prot_no: Q13472
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q13472/entry
  • Mouse_gene_id: 21975
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21975
  • Mouse_swiss_prot_no: O70157
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O70157
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
  • Rat_swiss_link: http://www.uniprot.org/uniprot/
  • 特异性: Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
  • 实测条带: 115kD
  • 信号通路: Homologous recombination;
  • 功能: catalytic activity:ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.,function:Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.,similarity:Belongs to the prokaryotic type I/III topoisomerase family.,subunit:Directly interacts with BLM and RMI1. Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.,tissue specificity:High expression is found in testis, heart, skeletal muscle and pancreas.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Mitochondrion matrix .
  • 组织表达: High expression is found in testis, heart, skeletal muscle and pancreas.
  • 科研货号: PLA019294
Topo IIIα Polyclonal Antibody
Catalog No PLA019294
Product information
  • 基因名称: TOP3A
  • 蛋白名称: DNA topoisomerase 3-alpha
  • Human_gene_id: 7156
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7156
  • Human_swiss_prot_no: Q13472
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q13472/entry
  • Mouse_gene_id: 21975
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21975
  • Mouse_swiss_prot_no: O70157
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O70157
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
  • Rat_swiss_link: http://www.uniprot.org/uniprot/
  • 特异性: Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
  • 实测条带: 115kD
  • 信号通路: Homologous recombination;
  • 功能: catalytic activity:ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.,function:Reduces the number of supercoils in a highly negatively supercoiled DNA. Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.,similarity:Belongs to the prokaryotic type I/III topoisomerase family.,subunit:Directly interacts with BLM and RMI1. Component of the RMI complex, containing at least TOP3A, RMI1 and RMI2. The RMI complex interacts with BLM.,tissue specificity:High expression is found in testis, heart, skeletal muscle and pancreas.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Mitochondrion matrix .
  • 组织表达: High expression is found in testis, heart, skeletal muscle and pancreas.
  • 科研货号: PLA019294
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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