Neuregulin-3 Polyclonal Antibody

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商品货号： PLA019277

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NRG3
蛋白名称： Pro-neuregulin-3 membrane-bound isoform
Human_gene_id： 10718
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10718
Human_swiss_prot_no： P56975
Human_swiss_link： http://www.uniprot.org/uniprotkb/P56975/entry
Mouse_gene_id： 18183
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18183
Mouse_swiss_prot_no： O35181
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35181
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特异性： Neuregulin-3 Polyclonal Antibody detects endogenous levels of Neuregulin-3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NRG3; Pro-neuregulin-3, membrane-bound isoform; Pro-NRG3
实测条带： 80kD
信号通路： ErbB_HER;
功能： developmental stage:Isoform 3 is expressed in fetal brain but not in other fetal tissues.,domain:ERBB receptor binding is elicited entirely by the EGF-like domain.,domain:The cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing involves initial intracellular domain dimerization.,function:Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.,PTM:Extensive glycosylation precedes the proteolytic cleavage (By similarity). Isoform 3 is glycosylated.,PTM:Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form.,similarity:Belongs to the neuregulin family.,similarity:Contains 1 EGF-like domain.,subcellular location:Does not seem to be active.,subcellular location:Isoform 3 is also proteolytically released as a soluble form.,tissue specificity:Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Pro-neuregulin-3, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-3]: Secreted .; [Isoform 3]: Cell membrane; Single-pass type I membrane protein. Isoform 3 is also proteolytically released as a soluble form.
组织表达： Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes.
科研货号： PLA019277

Neuregulin-3 Polyclonal Antibody

Catalog No PLA019277

Product information

基因名称： NRG3
蛋白名称： Pro-neuregulin-3 membrane-bound isoform
Human_gene_id： 10718
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10718
Human_swiss_prot_no： P56975
Human_swiss_link： http://www.uniprot.org/uniprotkb/P56975/entry
Mouse_gene_id： 18183
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18183
Mouse_swiss_prot_no： O35181
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35181
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=
Rat_swiss_link： http://www.uniprot.org/uniprot/
特异性： Neuregulin-3 Polyclonal Antibody detects endogenous levels of Neuregulin-3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NRG3; Pro-neuregulin-3, membrane-bound isoform; Pro-NRG3
实测条带： 80kD
信号通路： ErbB_HER;
功能： developmental stage:Isoform 3 is expressed in fetal brain but not in other fetal tissues.,domain:ERBB receptor binding is elicited entirely by the EGF-like domain.,domain:The cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing involves initial intracellular domain dimerization.,function:Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.,PTM:Extensive glycosylation precedes the proteolytic cleavage (By similarity). Isoform 3 is glycosylated.,PTM:Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form.,similarity:Belongs to the neuregulin family.,similarity:Contains 1 EGF-like domain.,subcellular location:Does not seem to be active.,subcellular location:Isoform 3 is also proteolytically released as a soluble form.,tissue specificity:Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Pro-neuregulin-3, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-3]: Secreted .; [Isoform 3]: Cell membrane; Single-pass type I membrane protein. Isoform 3 is also proteolytically released as a soluble form.
组织表达： Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes.
科研货号： PLA019277

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