其他名称: KIR2DL1; CD158A; NKAT1; Killer cell immunoglobulin-like receptor 2DL1; CD158 antigen-like family member A; MHC class I NK cell receptor; Natural killer-associated transcript 1; NKAT-1; p58 natural killer cell receptor clones CL-42/47.11; p58 NK receptor CL-42/47.11; p58.1 MHC class-I-specific NK receptor; CD158a
实测条带: 39kD
信号通路: Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease;
功能: function:Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.,miscellaneous:PubMed:15580659, identified a chromosomal rearrangement producing a recombinant gene composed of the promoter and first exon of KIR2DL5A fused to KIR3DP1 which was originally thought to be a pseudogene. This leads to the expression in 4.5 percent of a Spanish Caucasoid population of an mRNA which may encode a chimeric protein KIR2DL5A/KIR3DP1.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in peripheral blood cells.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein.
其他名称: KIR2DL1; CD158A; NKAT1; Killer cell immunoglobulin-like receptor 2DL1; CD158 antigen-like family member A; MHC class I NK cell receptor; Natural killer-associated transcript 1; NKAT-1; p58 natural killer cell receptor clones CL-42/47.11; p58 NK receptor CL-42/47.11; p58.1 MHC class-I-specific NK receptor; CD158a
实测条带: 39kD
信号通路: Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease;
功能: function:Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.,miscellaneous:PubMed:15580659, identified a chromosomal rearrangement producing a recombinant gene composed of the promoter and first exon of KIR2DL5A fused to KIR3DP1 which was originally thought to be a pseudogene. This leads to the expression in 4.5 percent of a Spanish Caucasoid population of an mRNA which may encode a chimeric protein KIR2DL5A/KIR3DP1.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in peripheral blood cells.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein.