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P-Selectin Polyclonal Antibody
商品货号: PLA019229
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: SELP
  • 蛋白名称: P-selectin
  • Human_gene_id: 6403
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6403
  • Human_swiss_prot_no: P16109
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P16109/entry
  • Mouse_gene_id: 20344
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20344
  • Mouse_swiss_prot_no: Q01102
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q01102
  • Rat_gene_id: 25651
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25651
  • Rat_swiss_prot_no: P98106
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P98106
  • 特异性: P-Selectin Polyclonal Antibody detects endogenous levels of P-Selectin protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: SELP; GMRP; GRMP; P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD62P
  • 实测条带: 91kD
  • 信号通路: Cell adhesion molecules (CAMs);
  • 功能: disease:Defects in SELP may be a cause of susceptibility to ischemic stroke [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.,function:Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.,online information:P-selectin,similarity:Belongs to the selectin/LECAM family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 9 Sushi (CCP/SCR) domains.,subunit:Interacts with SNX17. Interacts with PSGL1/SEPL and mediateS neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope and specific tyrosine sulfation on PSGL1.,tissue specificity:Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Single-pass type I membrane protein .
  • 组织表达: Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
  • 科研货号: PLA019229
P-Selectin Polyclonal Antibody
Catalog No PLA019229
Product information
  • 基因名称: SELP
  • 蛋白名称: P-selectin
  • Human_gene_id: 6403
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6403
  • Human_swiss_prot_no: P16109
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P16109/entry
  • Mouse_gene_id: 20344
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20344
  • Mouse_swiss_prot_no: Q01102
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q01102
  • Rat_gene_id: 25651
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25651
  • Rat_swiss_prot_no: P98106
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P98106
  • 特异性: P-Selectin Polyclonal Antibody detects endogenous levels of P-Selectin protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: SELP; GMRP; GRMP; P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD62P
  • 实测条带: 91kD
  • 信号通路: Cell adhesion molecules (CAMs);
  • 功能: disease:Defects in SELP may be a cause of susceptibility to ischemic stroke [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.,function:Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.,online information:P-selectin,similarity:Belongs to the selectin/LECAM family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 9 Sushi (CCP/SCR) domains.,subunit:Interacts with SNX17. Interacts with PSGL1/SEPL and mediateS neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope and specific tyrosine sulfation on PSGL1.,tissue specificity:Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane ; Single-pass type I membrane protein .
  • 组织表达: Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
  • 科研货号: PLA019229
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
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