GABAA Rα1 Polyclonal Antibody

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商品货号： PLA019209

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： GABRA1
蛋白名称： Gamma-aminobutyric acid receptor subunit alpha-1
Human_gene_id： 2554
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2554
Human_swiss_prot_no： P14867
Human_swiss_link： http://www.uniprot.org/uniprotkb/P14867/entry
Mouse_gene_id： 14394
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14394
Mouse_swiss_prot_no： P62812
Mouse_swiss_link： http://www.uniprot.org/uniprot/P62812
Rat_gene_id： 29705
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29705
Rat_swiss_prot_no： P62813
Rat_swiss_link： http://www.uniprot.org/uniprot/P62813
特异性： GABAA Rα1 Polyclonal Antibody detects endogenous levels of GABAA Rα1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： GABRA1; Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1
实测条带： 50kD
信号通路： Neuroactive ligand-receptor interaction;
功能： disease:Defects in GABRA1 are a cause of juvenile myoclonic epilepsy (EJM) [MIM:606904]. EJM is a subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.,disease:Defects in GABRA1 are the cause of childhood absence epilepsy type 4 (ECA4) [MIM:611136]. ECA4 is a subtype of idiopathic generalized epilepsy (IGE) characterized by onset at age 6-7 years, frequent absence seizures (several per day) and bilateral, synchronous, symmetric 3-Hz spike waves on EEG. During adolescence, tonic-clonic and myoclonic seizures develop. Absence seizures may either remit or persist into adulthood.,function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,online information:Forbidden fruit - Issue 56 of March 2005,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane .
组织表达： Brain,Cerebellum,Cerebrum,
科研货号： PLA019209

GABAA Rα1 Polyclonal Antibody

Catalog No PLA019209

Product information

基因名称： GABRA1
蛋白名称： Gamma-aminobutyric acid receptor subunit alpha-1
Human_gene_id： 2554
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2554
Human_swiss_prot_no： P14867
Human_swiss_link： http://www.uniprot.org/uniprotkb/P14867/entry
Mouse_gene_id： 14394
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14394
Mouse_swiss_prot_no： P62812
Mouse_swiss_link： http://www.uniprot.org/uniprot/P62812
Rat_gene_id： 29705
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29705
Rat_swiss_prot_no： P62813
Rat_swiss_link： http://www.uniprot.org/uniprot/P62813
特异性： GABAA Rα1 Polyclonal Antibody detects endogenous levels of GABAA Rα1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： GABRA1; Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1
实测条带： 50kD
信号通路： Neuroactive ligand-receptor interaction;
功能： disease:Defects in GABRA1 are a cause of juvenile myoclonic epilepsy (EJM) [MIM:606904]. EJM is a subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.,disease:Defects in GABRA1 are the cause of childhood absence epilepsy type 4 (ECA4) [MIM:611136]. ECA4 is a subtype of idiopathic generalized epilepsy (IGE) characterized by onset at age 6-7 years, frequent absence seizures (several per day) and bilateral, synchronous, symmetric 3-Hz spike waves on EEG. During adolescence, tonic-clonic and myoclonic seizures develop. Absence seizures may either remit or persist into adulthood.,function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,online information:Forbidden fruit - Issue 56 of March 2005,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane .
组织表达： Brain,Cerebellum,Cerebrum,
科研货号： PLA019209

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