PI 3-Kinase p110δ Polyclonal Antibody

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商品货号： PLA019185

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： PIK3CD
蛋白名称： Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Human_gene_id： 5293
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5293
Human_swiss_prot_no： O00329
Human_swiss_link： http://www.uniprot.org/uniprotkb/O00329/entry
Mouse_gene_id： 18707
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18707
Mouse_swiss_prot_no： O35904
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35904
特异性： PI 3-Kinase p110δ Polyclonal Antibody detects endogenous levels of PI 3-Kinase p110δ protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： PIK3CD; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110delta
实测条带： 120kD
信号通路： Inositol phosphate metabolism;ErbB_HER;Chemokine;Phosphatidylinositol signaling system;mTOR;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;VEGF;Focal adhesion;Toll_Like;Jak_STAT;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Neurotrophin;Regulates Actin and Cytoskeleton;Insulin_Receptor;Progesterone-mediated oocyte maturation;Type II diabetes mellitus;Aldosterone-regulated sodium reabsorption;Pathways in cancer;Colorectal cancer;Renal cell carcinoma;Pancreatic cancer;Endometrial cancer;Glioma;Prostate cancer;Melanoma;Chronic myeloid leukemia;Acute myeloid leukemia;Small cell lung cancer;Non-small cell lung cancer;
功能： catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.,pathway:Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.,PTM:Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Interacts with ERAS.,tissue specificity:Expressed predominantly in leukocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .
组织表达： In humans, the highest levels of expression are seen in peripheral blood mononuclear cells, spleen, and thymus, and low levels of expression in testes, uterus, colon, and small intestine but not in other tissues examined including prostate, heart, brain, and liver (PubMed:9235916). Isoform 2 is expressed in normal thymus, lung and spleen tissues, and is detected at low levels in normal lysates from colon and ovarian biopsies, at elevated levels in lysates from colorectal tumors and is abundantly expressed in some ovarian tumors (at protein level). Both isoform 1 and isoform 2 are widely expressed. Isoform 1 is expressed predominantly in leukocytes.
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科研货号： PLA019185

PI 3-Kinase p110δ Polyclonal Antibody

Catalog No PLA019185

Product information

基因名称： PIK3CD
蛋白名称： Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Human_gene_id： 5293
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5293
Human_swiss_prot_no： O00329
Human_swiss_link： http://www.uniprot.org/uniprotkb/O00329/entry
Mouse_gene_id： 18707
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18707
Mouse_swiss_prot_no： O35904
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35904
特异性： PI 3-Kinase p110δ Polyclonal Antibody detects endogenous levels of PI 3-Kinase p110δ protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： PIK3CD; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110delta
实测条带： 120kD
信号通路： Inositol phosphate metabolism;ErbB_HER;Chemokine;Phosphatidylinositol signaling system;mTOR;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;VEGF;Focal adhesion;Toll_Like;Jak_STAT;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Neurotrophin;Regulates Actin and Cytoskeleton;Insulin_Receptor;Progesterone-mediated oocyte maturation;Type II diabetes mellitus;Aldosterone-regulated sodium reabsorption;Pathways in cancer;Colorectal cancer;Renal cell carcinoma;Pancreatic cancer;Endometrial cancer;Glioma;Prostate cancer;Melanoma;Chronic myeloid leukemia;Acute myeloid leukemia;Small cell lung cancer;Non-small cell lung cancer;
功能： catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.,pathway:Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.,PTM:Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.,similarity:Belongs to the PI3/PI4-kinase family.,similarity:Contains 1 PI3K/PI4K domain.,subunit:Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Interacts with ERAS.,tissue specificity:Expressed predominantly in leukocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .
组织表达： In humans, the highest levels of expression are seen in peripheral blood mononuclear cells, spleen, and thymus, and low levels of expression in testes, uterus, colon, and small intestine but not in other tissues examined including prostate, heart, brain, and liver (PubMed:9235916). Isoform 2 is expressed in normal thymus, lung and spleen tissues, and is detected at low levels in normal lysates from colon and ovarian biopsies, at elevated levels in lysates from colorectal tumors and is abundantly expressed in some ovarian tumors (at protein level). Both isoform 1 and isoform 2 are widely expressed. Isoform 1 is expressed predominantly in leukocytes.
tag： hot
科研货号： PLA019185

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