功能: cofactor:Binds 1 zinc ion per trimer.,function:Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,tissue specificity:Widespread; most predominant in spleen, lung and prostate.,
相关产品: YT5511,YT4721,KE1068,KA3624C
细胞定位: Cell membrane ; Single-pass type II membrane protein . Secreted . Exists both as membrane-bound and soluble form. .
组织表达: Widespread; most predominant in spleen, lung and prostate.
科研货号: PLA019162
TRAIL Polyclonal Antibody
Catalog NoPLA019162
Product information
基因名称: TNFSF10
蛋白名称: Tumor necrosis factor ligand superfamily member 10
功能: cofactor:Binds 1 zinc ion per trimer.,function:Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,tissue specificity:Widespread; most predominant in spleen, lung and prostate.,
相关产品: YT5511,YT4721,KE1068,KA3624C
细胞定位: Cell membrane ; Single-pass type II membrane protein . Secreted . Exists both as membrane-bound and soluble form. .
组织表达: Widespread; most predominant in spleen, lung and prostate.