Rab 5A Polyclonal Antibody

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商品货号： PLA019122

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： RAB5A
蛋白名称： Ras-related protein Rab-5A
Human_gene_id： 5868
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5868
Human_swiss_prot_no： P20339
Human_swiss_link： http://www.uniprot.org/uniprotkb/P20339/entry
Mouse_gene_id： 271457
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=271457
Mouse_swiss_prot_no： Q9CQD1
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CQD1
特异性： Rab 5A Polyclonal Antibody detects endogenous levels of Rab 5A protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RAB5A; RAB5; Ras-related protein Rab-5A
实测条带： 24kD
信号通路： Endocytosis;Amyotrophic lateral sclerosis (ALS);
功能： enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Cytoplasmic vesicle . Cell projection, ruffle . Membrane . Cytoplasm, cytosol . Cytoplasmic vesicle, phagosome membrane . Endosome membrane . Enriched in stage I melanosomes (PubMed:17081065). Alternates between membrane-bound and cytosolic forms (Probable). .
组织表达： Brain,Cervix,Cervix carcinoma,Placenta,
科研货号： PLA019122

Rab 5A Polyclonal Antibody

Catalog No PLA019122

Product information

基因名称： RAB5A
蛋白名称： Ras-related protein Rab-5A
Human_gene_id： 5868
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5868
Human_swiss_prot_no： P20339
Human_swiss_link： http://www.uniprot.org/uniprotkb/P20339/entry
Mouse_gene_id： 271457
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=271457
Mouse_swiss_prot_no： Q9CQD1
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CQD1
特异性： Rab 5A Polyclonal Antibody detects endogenous levels of Rab 5A protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RAB5A; RAB5; Ras-related protein Rab-5A
实测条带： 24kD
信号通路： Endocytosis;Amyotrophic lateral sclerosis (ALS);
功能： enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Required for the fusion of plasma membranes and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Cytoplasmic vesicle . Cell projection, ruffle . Membrane . Cytoplasm, cytosol . Cytoplasmic vesicle, phagosome membrane . Endosome membrane . Enriched in stage I melanosomes (PubMed:17081065). Alternates between membrane-bound and cytosolic forms (Probable). .
组织表达： Brain,Cervix,Cervix carcinoma,Placenta,
科研货号： PLA019122

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