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Syntaxin 1 Polyclonal Antibody
商品货号: PLA019106
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: STX1A
  • 蛋白名称: Syntaxin-1A
  • Human_gene_id: 6804
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6804
  • Human_swiss_prot_no: Q16623
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q16623/entry
  • Mouse_gene_id: 20907
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20907
  • Mouse_swiss_prot_no: O35526
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O35526
  • Rat_gene_id: 116470
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116470
  • Rat_swiss_prot_no: P32851
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P32851
  • 特异性: Syntaxin 1 Polyclonal Antibody detects endogenous levels of Syntaxin 1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
  • 实测条带: 30kD
  • 信号通路: SNARE interactions in vesicular transport;
  • 功能: disease:Haploinsufficiency of STX1A may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,subunit:Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Binds SYTL4 and STXBP6. Found in a ternary complex with STX1A and SNAP25. Interacts with OTOF (By similarity). Found in a complex with VAMP8 and SNAP23. Interacts with VAPA and SYBU.,tissue specificity:Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.,
  • 相关产品: YT5440,YT4493,YP0569,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome . Cell membrane . Colocalizes with KCNB1 at the cell membrane. .; [Isoform 2]: Secreted .
  • 组织表达: [Isoform 1]: Highly expressed in embryonic spinal cord and ganglia and in adult cerebellum and cerebral cortex. ; [Isoform 2]: Expressed in heart, liver, fat, skeletal muscle, kidney and brain.
  • 科研货号: PLA019106
Syntaxin 1 Polyclonal Antibody
Catalog No PLA019106
Product information
  • 基因名称: STX1A
  • 蛋白名称: Syntaxin-1A
  • Human_gene_id: 6804
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6804
  • Human_swiss_prot_no: Q16623
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q16623/entry
  • Mouse_gene_id: 20907
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20907
  • Mouse_swiss_prot_no: O35526
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O35526
  • Rat_gene_id: 116470
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116470
  • Rat_swiss_prot_no: P32851
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P32851
  • 特异性: Syntaxin 1 Polyclonal Antibody detects endogenous levels of Syntaxin 1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
  • 实测条带: 30kD
  • 信号通路: SNARE interactions in vesicular transport;
  • 功能: disease:Haploinsufficiency of STX1A may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,subunit:Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Binds SYTL4 and STXBP6. Found in a ternary complex with STX1A and SNAP25. Interacts with OTOF (By similarity). Found in a complex with VAMP8 and SNAP23. Interacts with VAPA and SYBU.,tissue specificity:Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.,
  • 相关产品: YT5440,YT4493,YP0569,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome . Cell membrane . Colocalizes with KCNB1 at the cell membrane. .; [Isoform 2]: Secreted .
  • 组织表达: [Isoform 1]: Highly expressed in embryonic spinal cord and ganglia and in adult cerebellum and cerebral cortex. ; [Isoform 2]: Expressed in heart, liver, fat, skeletal muscle, kidney and brain.
  • 科研货号: PLA019106
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
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