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IDH1 Polyclonal Antibody
商品货号: PLA019093
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: IDH1
  • 蛋白名称: Isocitrate dehydrogenase [NADP] cytoplasmic
  • Human_gene_id: 3417
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3417
  • Human_swiss_prot_no: O75874
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O75874/entry
  • Mouse_gene_id: 15926
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15926
  • Mouse_swiss_prot_no: O88844
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O88844
  • Rat_gene_id: 24479
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24479
  • Rat_swiss_prot_no: P41562
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P41562
  • 特异性: IDH1 Polyclonal Antibody detects endogenous levels of IDH1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: IDH1; PICD; Isocitrate dehydrogenase [NADP] cytoplasmic; IDH; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
  • 实测条带: 46kD
  • 信号通路: Citrate cycle (TCA cycle);Glutathione metabolism;
  • 功能: catalytic activity:Isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.,catalytic activity:Oxalosuccinate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.,cofactor:Binds 1 magnesium or manganese ion per subunit.,disease:Defects in IDH1 are a cause of glioblastoma multiforme (GBM) [MIM:137800]; also called familial glioma of brain. Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, and ependymomas.,miscellaneous:Cancer mutations affecting Arg-132 are tissue-specific, and suggest that this residue plays a unique role in the development of high-grade gliomas.,online information:Isocitrate dehydrogenase entry,similarity:Belongs to the isocitrate and isopropylmalate dehydrogenases family.,subunit:Homodimer.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm, cytosol . Peroxisome .
  • 组织表达: Brain,Cajal-Retzius cell,Fetal brain cortex,Human endometri
  • tag: hot
  • 科研货号: PLA019093
IDH1 Polyclonal Antibody
Catalog No PLA019093
Product information
  • 基因名称: IDH1
  • 蛋白名称: Isocitrate dehydrogenase [NADP] cytoplasmic
  • Human_gene_id: 3417
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3417
  • Human_swiss_prot_no: O75874
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O75874/entry
  • Mouse_gene_id: 15926
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15926
  • Mouse_swiss_prot_no: O88844
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O88844
  • Rat_gene_id: 24479
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24479
  • Rat_swiss_prot_no: P41562
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P41562
  • 特异性: IDH1 Polyclonal Antibody detects endogenous levels of IDH1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: IDH1; PICD; Isocitrate dehydrogenase [NADP] cytoplasmic; IDH; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
  • 实测条带: 46kD
  • 信号通路: Citrate cycle (TCA cycle);Glutathione metabolism;
  • 功能: catalytic activity:Isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.,catalytic activity:Oxalosuccinate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.,cofactor:Binds 1 magnesium or manganese ion per subunit.,disease:Defects in IDH1 are a cause of glioblastoma multiforme (GBM) [MIM:137800]; also called familial glioma of brain. Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, and ependymomas.,miscellaneous:Cancer mutations affecting Arg-132 are tissue-specific, and suggest that this residue plays a unique role in the development of high-grade gliomas.,online information:Isocitrate dehydrogenase entry,similarity:Belongs to the isocitrate and isopropylmalate dehydrogenases family.,subunit:Homodimer.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm, cytosol . Peroxisome .
  • 组织表达: Brain,Cajal-Retzius cell,Fetal brain cortex,Human endometri
  • tag: hot
  • 科研货号: PLA019093
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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