gp91-phox Polyclonal Antibody

> > > >

商品货号： PLA019063

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： CYBB
蛋白名称： Cytochrome b-245 heavy chain
Human_gene_id： 1536
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1536
Human_swiss_prot_no： P04839
Human_swiss_link： http://www.uniprot.org/uniprotkb/P04839/entry
Mouse_swiss_prot_no： Q61093
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61093
特异性： gp91-phox Polyclonal Antibody detects endogenous levels of gp91-phox protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CYBB; NOX2; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome
实测条带： 70kD
信号通路： Leukocyte transendothelial migration;
功能： cofactor:FAD.,disease:Defects in CYBB are a cause of chronic granulomatous disease X-linked (XCGD) [MIM:306400]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.,function:Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.,online information:CYBB deficiency database,PTM:Glycosylated.,similarity:Contains 1 FAD-binding FR-type domain.,similarity:Contains 1 ferric oxidoreductase domain.,subunit:Composed of a heavy chain (beta) and a light chain (alpha).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein. As unassembled monomer may localize to the endoplasmic reticulum. .
组织表达： Detected in neutrophils (at protein level).
tag： hot
科研货号： PLA019063

gp91-phox Polyclonal Antibody

Catalog No PLA019063

Product information

基因名称： CYBB
蛋白名称： Cytochrome b-245 heavy chain
Human_gene_id： 1536
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1536
Human_swiss_prot_no： P04839
Human_swiss_link： http://www.uniprot.org/uniprotkb/P04839/entry
Mouse_swiss_prot_no： Q61093
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61093
特异性： gp91-phox Polyclonal Antibody detects endogenous levels of gp91-phox protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CYBB; NOX2; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome
实测条带： 70kD
信号通路： Leukocyte transendothelial migration;
功能： cofactor:FAD.,disease:Defects in CYBB are a cause of chronic granulomatous disease X-linked (XCGD) [MIM:306400]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.,function:Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.,online information:CYBB deficiency database,PTM:Glycosylated.,similarity:Contains 1 FAD-binding FR-type domain.,similarity:Contains 1 ferric oxidoreductase domain.,subunit:Composed of a heavy chain (beta) and a light chain (alpha).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein. As unassembled monomer may localize to the endoplasmic reticulum. .
组织表达： Detected in neutrophils (at protein level).
tag： hot
科研货号： PLA019063

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.