Troponin T-C Polyclonal Antibody

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商品货号： PLA019043

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： TNNT2
蛋白名称： Troponin T cardiac muscle
Human_gene_id： 7139
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7139
Human_swiss_prot_no： P45379
Human_swiss_link： http://www.uniprot.org/uniprotkb/P45379/entry
Mouse_gene_id： 21956
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21956
Mouse_swiss_prot_no： P50752
Mouse_swiss_link： http://www.uniprot.org/uniprot/P50752
Rat_gene_id： 24837
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24837
Rat_swiss_prot_no： P50753
Rat_swiss_link： http://www.uniprot.org/uniprot/P50753
特异性： Troponin T-C Polyclonal Antibody detects endogenous levels of Troponin T-C protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TNNT2; Troponin T, cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT
实测条带： 35kD
信号通路： Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;
功能： alternative products:Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,disease:Defects in TNNT2 are the cause of cardiomyopathy dilated type 1D (CMD1D) [MIM:601494]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.,disease:Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2) [MIM:115195]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.,disease:Defects in TNNT2 are the cause of cardiomyopathy familial restrictive type 3 (RCM3) [MIM:612422]. Restrictive cardiomyopathy is a heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.,function:Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.,similarity:Belongs to the troponin T family.,tissue specificity:Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytosol,troponin complex,striated muscle thin filament,sarcomere,
组织表达： Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
科研货号： PLA019043

Troponin T-C Polyclonal Antibody

Catalog No PLA019043

Product information

基因名称： TNNT2
蛋白名称： Troponin T cardiac muscle
Human_gene_id： 7139
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7139
Human_swiss_prot_no： P45379
Human_swiss_link： http://www.uniprot.org/uniprotkb/P45379/entry
Mouse_gene_id： 21956
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21956
Mouse_swiss_prot_no： P50752
Mouse_swiss_link： http://www.uniprot.org/uniprot/P50752
Rat_gene_id： 24837
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24837
Rat_swiss_prot_no： P50753
Rat_swiss_link： http://www.uniprot.org/uniprot/P50753
特异性： Troponin T-C Polyclonal Antibody detects endogenous levels of Troponin T-C protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TNNT2; Troponin T, cardiac muscle; TnTc; Cardiac muscle troponin T; cTnT
实测条带： 35kD
信号通路： Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;
功能： alternative products:Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,disease:Defects in TNNT2 are the cause of cardiomyopathy dilated type 1D (CMD1D) [MIM:601494]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.,disease:Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2) [MIM:115195]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.,disease:Defects in TNNT2 are the cause of cardiomyopathy familial restrictive type 3 (RCM3) [MIM:612422]. Restrictive cardiomyopathy is a heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.,function:Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.,similarity:Belongs to the troponin T family.,tissue specificity:Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytosol,troponin complex,striated muscle thin filament,sarcomere,
组织表达： Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
科研货号： PLA019043

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