功能: function:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds IL1RAP.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane ; Single-pass type I membrane protein . Cell membrane . Secreted .
组织表达: Expressed in T-helper cell subsets. Preferentially expressed in T-helper 1 (Th1) cells.
功能: function:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds IL1RAP.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane ; Single-pass type I membrane protein . Cell membrane . Secreted .
组织表达: Expressed in T-helper cell subsets. Preferentially expressed in T-helper 1 (Th1) cells.