Neuregulin-2 Polyclonal Antibody

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商品货号： PLA018924

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NRG2
蛋白名称： Pro-neuregulin-2 membrane-bound isoform
Human_gene_id： 9542
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9542
Human_swiss_prot_no： O14511
Human_swiss_link： http://www.uniprot.org/uniprotkb/O14511/entry
Mouse_swiss_prot_no： P56974
Mouse_swiss_link： http://www.uniprot.org/uniprot/P56974
Rat_gene_id： 432361
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=432361
Rat_swiss_prot_no： O35569
Rat_swiss_link： http://www.uniprot.org/uniprot/O35569
特异性： Neuregulin-2 Polyclonal Antibody detects endogenous levels of Neuregulin-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NRG2; NTAK; Pro-neuregulin-2, membrane-bound isoform; Pro-NRG2
实测条带： 90kD
信号通路： ErbB_HER;
功能： domain:ERBB receptor binding is elicited entirely by the EGF-like domain.,domain:The cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing involves initial intracellular domain dimerization.,function:Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.,PTM:Extensive glycosylation precedes the proteolytic cleavage.,PTM:Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form.,similarity:Belongs to the neuregulin family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,subcellular location:Does not seem to be active.,tissue specificity:Restricted to the cerebellum in the adult.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Pro-neuregulin-2, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-2]: Secreted .
组织表达： Restricted to the cerebellum in the adult.
科研货号： PLA018924

Neuregulin-2 Polyclonal Antibody

Catalog No PLA018924

Product information

基因名称： NRG2
蛋白名称： Pro-neuregulin-2 membrane-bound isoform
Human_gene_id： 9542
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9542
Human_swiss_prot_no： O14511
Human_swiss_link： http://www.uniprot.org/uniprotkb/O14511/entry
Mouse_swiss_prot_no： P56974
Mouse_swiss_link： http://www.uniprot.org/uniprot/P56974
Rat_gene_id： 432361
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=432361
Rat_swiss_prot_no： O35569
Rat_swiss_link： http://www.uniprot.org/uniprot/O35569
特异性： Neuregulin-2 Polyclonal Antibody detects endogenous levels of Neuregulin-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NRG2; NTAK; Pro-neuregulin-2, membrane-bound isoform; Pro-NRG2
实测条带： 90kD
信号通路： ErbB_HER;
功能： domain:ERBB receptor binding is elicited entirely by the EGF-like domain.,domain:The cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing involves initial intracellular domain dimerization.,function:Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.,PTM:Extensive glycosylation precedes the proteolytic cleavage.,PTM:Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form.,similarity:Belongs to the neuregulin family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,subcellular location:Does not seem to be active.,tissue specificity:Restricted to the cerebellum in the adult.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Pro-neuregulin-2, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-2]: Secreted .
组织表达： Restricted to the cerebellum in the adult.
科研货号： PLA018924

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