其他名称: GPC3; OCI5; Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7
实测条带: 70kD
功能: disease:Defects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.,function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan that bears heparan sulfate. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.,similarity:Belongs to the glypican family.,tissue specificity:Highly expressed in lung, liver and kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .
其他名称: GPC3; OCI5; Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7
实测条带: 70kD
功能: disease:Defects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.,function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan that bears heparan sulfate. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.,similarity:Belongs to the glypican family.,tissue specificity:Highly expressed in lung, liver and kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .