其他名称： TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; Tumor necrosis factor receptor superfamily member 25; Apo-3; Apoptosis-inducing receptor AIR;Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death receptor 3; Lymphocyte-associated receptor of death; LARD; Protein WSL; Protein WSL-1
实测条带： 45kD
信号通路： Cytokine-cytokine receptor interaction;
功能： function:Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.,PTM:Glycosylated.,similarity:Contains 1 death domain.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Homodimer. Interacts strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. Interacts with BAG4.,tissue specificity:Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 9]: Cell membrane; Single-pass type I membrane protein.; [Isoform 11]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.; [Isoform 7]: Secreted.; [Isoform 8]: Secreted.; [Isoform 10]: Secreted.; [Isoform 12]: Secreted.
组织表达： Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
科研货号： PLA018857
DR3 Polyclonal Antibody
Catalog NoPLA018857
Product information
基因名称： TNFRSF25
蛋白名称： Tumor necrosis factor receptor superfamily member 25
其他名称： TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; Tumor necrosis factor receptor superfamily member 25; Apo-3; Apoptosis-inducing receptor AIR;Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death receptor 3; Lymphocyte-associated receptor of death; LARD; Protein WSL; Protein WSL-1
实测条带： 45kD
信号通路： Cytokine-cytokine receptor interaction;
功能： function:Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.,PTM:Glycosylated.,similarity:Contains 1 death domain.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Homodimer. Interacts strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. Interacts with BAG4.,tissue specificity:Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 9]: Cell membrane; Single-pass type I membrane protein.; [Isoform 11]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.; [Isoform 7]: Secreted.; [Isoform 8]: Secreted.; [Isoform 10]: Secreted.; [Isoform 12]: Secreted.
组织表达： Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
在线咨询
湘公网安备