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VAV1 Polyclonal Antibody
商品货号: PLA018775
适 应 性: 人,小鼠,大鼠
WB IF ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: VAV1
  • 蛋白名称: Proto-oncogene vav
  • Human_gene_id: 7409
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7409
  • Human_swiss_prot_no: P15498
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P15498/entry
  • Mouse_gene_id: 22324
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22324
  • Mouse_swiss_prot_no: P27870
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P27870
  • Rat_swiss_prot_no: P54100
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P54100
  • 特异性: VAV1 Polyclonal Antibody detects endogenous levels of VAV1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: VAV1; VAV; Proto-oncogene vav
  • 实测条带: 98kD
  • 信号通路: Chemokine;Focal adhesion;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;
  • 功能: domain:The DH domain is involved in interaction with CCPG1.,function:Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.,miscellaneous:'Vav' stands for the sixth letter of the Hebrew alphabet.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:May interact with CCPG1 (By similarity). Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK.,tissue specificity:Widely expressed in hematopoietic cells but not in other cell types.,
  • 相关产品: YT5041,YT4863,YT4862,YP0969,YP0274,YP0273,KA4316C,KA1228C
  • 细胞定位: intracellular,cytosol,plasma membrane,cell-cell junction,
  • 组织表达: Widely expressed in hematopoietic cells but not in other cell types.
  • 科研货号: PLA018775
VAV1 Polyclonal Antibody
Catalog No PLA018775
Product information
  • 基因名称: VAV1
  • 蛋白名称: Proto-oncogene vav
  • Human_gene_id: 7409
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7409
  • Human_swiss_prot_no: P15498
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P15498/entry
  • Mouse_gene_id: 22324
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22324
  • Mouse_swiss_prot_no: P27870
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P27870
  • Rat_swiss_prot_no: P54100
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P54100
  • 特异性: VAV1 Polyclonal Antibody detects endogenous levels of VAV1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: VAV1; VAV; Proto-oncogene vav
  • 实测条带: 98kD
  • 信号通路: Chemokine;Focal adhesion;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;
  • 功能: domain:The DH domain is involved in interaction with CCPG1.,function:Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.,miscellaneous:'Vav' stands for the sixth letter of the Hebrew alphabet.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:May interact with CCPG1 (By similarity). Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK.,tissue specificity:Widely expressed in hematopoietic cells but not in other cell types.,
  • 相关产品: YT5041,YT4863,YT4862,YP0969,YP0274,YP0273,KA4316C,KA1228C
  • 细胞定位: intracellular,cytosol,plasma membrane,cell-cell junction,
  • 组织表达: Widely expressed in hematopoietic cells but not in other cell types.
  • 科研货号: PLA018775
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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