β-1,4-Gal-T1 Polyclonal Antibody

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商品货号： PLA018747

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： B4GALT1
蛋白名称： Beta-1,4-galactosyltransferase 1
Human_gene_id： 2683
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2683
Human_swiss_prot_no： P15291
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15291/entry
Mouse_gene_id： 14595
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14595
Mouse_swiss_prot_no： P15535
Mouse_swiss_link： http://www.uniprot.org/uniprot/P15535
特异性： β-1,4-Gal-T1 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： B4GALT1; GGTB2; Beta-1; 4-galactosyltransferase 1; Beta-1,4-GalTase 1; Beta4Gal-T1; b4Gal-T1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
实测条带： 50kD
信号通路： Galactose metabolism;N-Glycan biosynthesis;Keratan sulfate biosynthesis;Glycosphingolipid biosynthesis;
功能： catalytic activity:UDP-galactose + D-glucose = UDP + lactose.,catalytic activity:UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.,catalytic activity:UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.,cofactor:Manganese.,disease:Defects in B4GALT1 are the cause of congenital disorder of glycosylation type 2D (CDG2D) [MIM:607091]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.,function:The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.,function:The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.,online information:Beta-1,4-galactosyltransferase 1,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,PTM:The soluble form derives from the membrane forms by proteolytic processing.,similarity:Belongs to the glycosyltransferase 7 family.,subcellular location:Found in trans cisternae of Golgi.,subcellular location:Soluble form found in body fluids.,subunit:Homodimer; and heterodimer with alpha-lactabulmin to form lactose synthase.,tissue specificity:Ubiquitously expressed, but at very low levels in fetal and adult brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform Long]: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Cell membrane ; Single-pass type II membrane protein. Cell surface . Cell projection, filopodium . Found in trans cisternae of Golgi but is mainly localized at the plasma membrane (PubMed:1714903). B4GALT1 cell surface expression is regulated by UBE2Q1 (By similarity). .; [Isoform Short]: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Found in trans cisternae of Golgi. .; [Processed beta-1,4-galactosyltransferase 1]: Secreted . Soluble form found in body fluids. .
组织表达： Ubiquitously expressed, but at very low levels in fetal and adult brain.
科研货号： PLA018747

β-1,4-Gal-T1 Polyclonal Antibody

Catalog No PLA018747

Product information

基因名称： B4GALT1
蛋白名称： Beta-1,4-galactosyltransferase 1
Human_gene_id： 2683
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2683
Human_swiss_prot_no： P15291
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15291/entry
Mouse_gene_id： 14595
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14595
Mouse_swiss_prot_no： P15535
Mouse_swiss_link： http://www.uniprot.org/uniprot/P15535
特异性： β-1,4-Gal-T1 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T1 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： B4GALT1; GGTB2; Beta-1; 4-galactosyltransferase 1; Beta-1,4-GalTase 1; Beta4Gal-T1; b4Gal-T1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
实测条带： 50kD
信号通路： Galactose metabolism;N-Glycan biosynthesis;Keratan sulfate biosynthesis;Glycosphingolipid biosynthesis;
功能： catalytic activity:UDP-galactose + D-glucose = UDP + lactose.,catalytic activity:UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.,catalytic activity:UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.,cofactor:Manganese.,disease:Defects in B4GALT1 are the cause of congenital disorder of glycosylation type 2D (CDG2D) [MIM:607091]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.,function:The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.,function:The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.,online information:Beta-1,4-galactosyltransferase 1,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,PTM:The soluble form derives from the membrane forms by proteolytic processing.,similarity:Belongs to the glycosyltransferase 7 family.,subcellular location:Found in trans cisternae of Golgi.,subcellular location:Soluble form found in body fluids.,subunit:Homodimer; and heterodimer with alpha-lactabulmin to form lactose synthase.,tissue specificity:Ubiquitously expressed, but at very low levels in fetal and adult brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform Long]: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Cell membrane ; Single-pass type II membrane protein. Cell surface . Cell projection, filopodium . Found in trans cisternae of Golgi but is mainly localized at the plasma membrane (PubMed:1714903). B4GALT1 cell surface expression is regulated by UBE2Q1 (By similarity). .; [Isoform Short]: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Found in trans cisternae of Golgi. .; [Processed beta-1,4-galactosyltransferase 1]: Secreted . Soluble form found in body fluids. .
组织表达： Ubiquitously expressed, but at very low levels in fetal and adult brain.
科研货号： PLA018747

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