其他名称： ZP2; ZPA; Zona pellucida sperm-binding protein 2; Zona pellucida glycoprotein 2; Zp-2; Zona pellucida protein A
分子量： 82kD
功能： developmental stage:Expressed during the 2-week growth phase of oogenesis, prior to ovulation.,domain:The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.,function:The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor.,PTM:O-glycosylated; contains sulfate-substituted glycans.,PTM:Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.,PTM:Proteolytically cleaved in the N-terminal part after fertilization, yielding a N-terminal peptide of about 30 kDa which remains covalently attached to the C-terminal peptide via disulfide bond(s). This cleavage may play an important role in the post-fertilization block to polyspermy.,similarity:Belongs to the ZP domain family. ZPA subfamily.,similarity:Contains 1 ZP domain.,subunit:Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers.,tissue specificity:Oocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Processed zona pellucida sperm-binding protein 2]: Zona pellucida .; Cell membrane ; Single-pass type I membrane protein .
其他名称： ZP2; ZPA; Zona pellucida sperm-binding protein 2; Zona pellucida glycoprotein 2; Zp-2; Zona pellucida protein A
分子量： 82kD
功能： developmental stage:Expressed during the 2-week growth phase of oogenesis, prior to ovulation.,domain:The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.,function:The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor.,PTM:O-glycosylated; contains sulfate-substituted glycans.,PTM:Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.,PTM:Proteolytically cleaved in the N-terminal part after fertilization, yielding a N-terminal peptide of about 30 kDa which remains covalently attached to the C-terminal peptide via disulfide bond(s). This cleavage may play an important role in the post-fertilization block to polyspermy.,similarity:Belongs to the ZP domain family. ZPA subfamily.,similarity:Contains 1 ZP domain.,subunit:Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers.,tissue specificity:Oocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Processed zona pellucida sperm-binding protein 2]: Zona pellucida .; Cell membrane ; Single-pass type I membrane protein .
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