其他名称： XRCC2; DNA repair protein XRCC2; X-ray repair cross-complementing protein 2
实测条带： 32kD
信号通路： Homologous recombination;
功能： function:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51D. Part of a BCDX2 complex consisting of RAD51B, RAD51C, RAD51D and XRCC2. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3. In the absence of DNA, XRCC2-RAD51D formed a multimeric ring structure. In the presence of single-stranded DNA, XRCC2-RAD51D formed a filamentous structure.,
相关产品： YT4918,KA3433C,RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
其他名称： XRCC2; DNA repair protein XRCC2; X-ray repair cross-complementing protein 2
实测条带： 32kD
信号通路： Homologous recombination;
功能： function:Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the recA family. RAD51 subfamily.,subunit:Interacts with RAD51D. Part of a BCDX2 complex consisting of RAD51B, RAD51C, RAD51D and XRCC2. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3. In the absence of DNA, XRCC2-RAD51D formed a multimeric ring structure. In the presence of single-stranded DNA, XRCC2-RAD51D formed a filamentous structure.,
相关产品： YT4918,KA3433C,RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
在线咨询
湘公网安备