Versican Polyclonal Antibody

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商品货号： PLA018625

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： VCAN
蛋白名称： Versican core protein
Human_gene_id： 1462
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1462
Human_swiss_prot_no： P13611
Human_swiss_link： http://www.uniprot.org/uniprotkb/P13611/entry
Mouse_swiss_prot_no： Q62059
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q62059
特异性： Versican Polyclonal Antibody detects endogenous levels of Versican protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： VCAN; CSPG2; Versican core protein; Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Glial hyaluronate-binding protein; GHAP; Large fibroblast proteoglycan; PG-M
分子量： 373kD
信号通路： Cell adhesion molecules (CAMs);
功能： alternative products:Additional isoforms seem to exist,developmental stage:Disappears after the cartilage development.,disease:Defects in VCAN are the cause of Wagner syndrome type 1 (WGN1) [MIM:143200]. WGN is a dominantly inherited vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. Systemic manifestations are absent in WGN.,function:May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.,online information:Versican,similarity:Belongs to the aggrecan/versican proteoglycan family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 2 Link domains.,subunit:Interacts with FBLN1.,tissue specificity:Cerebral white matter. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas; isoform V2 is restricted to normal brain and gliomas; isoform V3 is found in all these tissues except medulloblastomas.,
相关产品： YT5917,YT4874,RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted, extracellular space, extracellular matrix . Cell projection, cilium, photoreceptor outer segment . Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix .
组织表达： Expressed in the retina (at protein level) (PubMed:29777959). Cerebral white matter and plasma (PubMed:2469524). Isoform V0: Expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas (PubMed:8627343). Isoform V1: Expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas (PubMed:8627343). Isoform V2: Restricted to normal brain and gliomas (PubMed:8627343). Isoform V3: Found in all these tissues except medulloblastomas (PubMed:8627343).
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科研货号： PLA018625

Versican Polyclonal Antibody

Catalog No PLA018625

Product information

基因名称： VCAN
蛋白名称： Versican core protein
Human_gene_id： 1462
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1462
Human_swiss_prot_no： P13611
Human_swiss_link： http://www.uniprot.org/uniprotkb/P13611/entry
Mouse_swiss_prot_no： Q62059
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q62059
特异性： Versican Polyclonal Antibody detects endogenous levels of Versican protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： VCAN; CSPG2; Versican core protein; Chondroitin sulfate proteoglycan core protein 2; Chondroitin sulfate proteoglycan 2; Glial hyaluronate-binding protein; GHAP; Large fibroblast proteoglycan; PG-M
分子量： 373kD
信号通路： Cell adhesion molecules (CAMs);
功能： alternative products:Additional isoforms seem to exist,developmental stage:Disappears after the cartilage development.,disease:Defects in VCAN are the cause of Wagner syndrome type 1 (WGN1) [MIM:143200]. WGN is a dominantly inherited vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. Systemic manifestations are absent in WGN.,function:May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.,online information:Versican,similarity:Belongs to the aggrecan/versican proteoglycan family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 2 Link domains.,subunit:Interacts with FBLN1.,tissue specificity:Cerebral white matter. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas; isoform V2 is restricted to normal brain and gliomas; isoform V3 is found in all these tissues except medulloblastomas.,
相关产品： YT5917,YT4874,RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted, extracellular space, extracellular matrix . Cell projection, cilium, photoreceptor outer segment . Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix .
组织表达： Expressed in the retina (at protein level) (PubMed:29777959). Cerebral white matter and plasma (PubMed:2469524). Isoform V0: Expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas (PubMed:8627343). Isoform V1: Expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas (PubMed:8627343). Isoform V2: Restricted to normal brain and gliomas (PubMed:8627343). Isoform V3: Found in all these tissues except medulloblastomas (PubMed:8627343).
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科研货号： PLA018625

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