TXA synthase Polyclonal Antibody

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商品货号： PLA018543

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： TBXAS1
蛋白名称： Thromboxane-A synthase
Human_gene_id： 6916
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6916
Human_swiss_prot_no： P24557
Human_swiss_link： http://www.uniprot.org/uniprotkb/P24557/entry
Mouse_swiss_prot_no： P36423
Mouse_swiss_link： http://www.uniprot.org/uniprot/P36423
特异性： TXA synthase Polyclonal Antibody detects endogenous levels of TXA synthase protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TBXAS1; CYP5; CYP5A1; Thromboxane-A synthase; TXA synthase; TXS; Cytochrome P450 5A1
实测条带： 60kD
信号通路： Arachidonic acid metabolism;
功能： catalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,11-alpha-epoxy-15-hydroxythromboxa-5,13-dienoate.,cofactor:Heme group.,disease:Defects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.,disease:Defects in TBXAS1 are the cause of thromboxane synthetase deficiency [MIM:274180]. It is characterized by hemorrhagic diathesis.,online information:CYP5A1 alleles,similarity:Belongs to the cytochrome P450 family.,subunit:Monomer.,tissue specificity:Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
组织表达： Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
科研货号： PLA018543

TXA synthase Polyclonal Antibody

Catalog No PLA018543

Product information

基因名称： TBXAS1
蛋白名称： Thromboxane-A synthase
Human_gene_id： 6916
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6916
Human_swiss_prot_no： P24557
Human_swiss_link： http://www.uniprot.org/uniprotkb/P24557/entry
Mouse_swiss_prot_no： P36423
Mouse_swiss_link： http://www.uniprot.org/uniprot/P36423
特异性： TXA synthase Polyclonal Antibody detects endogenous levels of TXA synthase protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TBXAS1; CYP5; CYP5A1; Thromboxane-A synthase; TXA synthase; TXS; Cytochrome P450 5A1
实测条带： 60kD
信号通路： Arachidonic acid metabolism;
功能： catalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,11-alpha-epoxy-15-hydroxythromboxa-5,13-dienoate.,cofactor:Heme group.,disease:Defects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.,disease:Defects in TBXAS1 are the cause of thromboxane synthetase deficiency [MIM:274180]. It is characterized by hemorrhagic diathesis.,online information:CYP5A1 alleles,similarity:Belongs to the cytochrome P450 family.,subunit:Monomer.,tissue specificity:Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Multi-pass membrane protein .
组织表达： Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
科研货号： PLA018543

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