其他名称： TRADD; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain
功能： domain:Requires the intact DEATH domain to associate with TNFRSF1A/TNFR1.,function:Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.,similarity:Contains 1 death domain.,subunit:Heterodimer with TNFRSF1A/TNFR1. Interacts with DAB2IP, FADD, HIPK2, KRT14, KRT16, KRT17, KRT18, RIPK1, SQSTM1, TRAF1, TRAF2 and TRPC4AP.,tissue specificity:Found in all examined tissues.,
相关产品： YT4716,KA3419C,RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Shuttles between the cytoplasm and the nucleus. .
组织表达： Found in all examined tissues.
科研货号： PLA018471
TRADD Polyclonal Antibody
Catalog NoPLA018471
Product information
基因名称： TRADD
蛋白名称： Tumor necrosis factor receptor type 1-associated DEATH domain protein
其他名称： TRADD; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain
功能： domain:Requires the intact DEATH domain to associate with TNFRSF1A/TNFR1.,function:Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.,similarity:Contains 1 death domain.,subunit:Heterodimer with TNFRSF1A/TNFR1. Interacts with DAB2IP, FADD, HIPK2, KRT14, KRT16, KRT17, KRT18, RIPK1, SQSTM1, TRAF1, TRAF2 and TRPC4AP.,tissue specificity:Found in all examined tissues.,
相关产品： YT4716,KA3419C,RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Shuttles between the cytoplasm and the nucleus. .
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