TNF-R2 Polyclonal Antibody

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商品货号： PLA018446

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： TNFRSF1B
蛋白名称： Tumor necrosis factor receptor superfamily member 1B
Human_gene_id： 7133
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7133
Human_swiss_prot_no： P20333
Human_swiss_link： http://www.uniprot.org/uniprotkb/P20333/entry
Mouse_gene_id： 21938
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21938
Mouse_swiss_prot_no： P25119
Mouse_swiss_link： http://www.uniprot.org/uniprot/P25119
Rat_gene_id： 156767
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=156767
Rat_swiss_prot_no： Q80WY6
Rat_swiss_link： http://www.uniprot.org/uniprot/Q80WY6
特异性： TNF-R2 Polyclonal Antibody detects endogenous levels of TNF-R2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TNFRSF1B; TNFBR; TNFR2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD antigen CD120b; Etanercept
实测条带： 48kD
信号通路： Cytokine-cytokine receptor interaction;Adipocytokine;Amyotrophic lateral sclerosis (ALS);
功能： function:Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.,online information:Clinical information on Enbrel,pharmaceutical:Available under the name Enbrel (Immunex and Wyeth-Ayerst). Used to treat moderate to severe rheumatoid arthritis (RA). Enbrel consist of the extracellular ligand-binding portion of TNFRSF1B linked to an immunoglobulin Fc chain. It binds to TNF-alpha and blocks its interactions with receptors.,PTM:A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by proteolytic processing.,PTM:Phosphorylated; mainly on serine residues and with a very low level on threonine residues.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Binds to TRAF2.,
相关产品： YT4688,KE1250,KA3559C,RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Tumor necrosis factor-binding protein 2]: Secreted.
组织表达： Muscle,PNS,Urine,
tag： hot
科研货号： PLA018446

TNF-R2 Polyclonal Antibody

Catalog No PLA018446

Product information

基因名称： TNFRSF1B
蛋白名称： Tumor necrosis factor receptor superfamily member 1B
Human_gene_id： 7133
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7133
Human_swiss_prot_no： P20333
Human_swiss_link： http://www.uniprot.org/uniprotkb/P20333/entry
Mouse_gene_id： 21938
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21938
Mouse_swiss_prot_no： P25119
Mouse_swiss_link： http://www.uniprot.org/uniprot/P25119
Rat_gene_id： 156767
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=156767
Rat_swiss_prot_no： Q80WY6
Rat_swiss_link： http://www.uniprot.org/uniprot/Q80WY6
特异性： TNF-R2 Polyclonal Antibody detects endogenous levels of TNF-R2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TNFRSF1B; TNFBR; TNFR2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD antigen CD120b; Etanercept
实测条带： 48kD
信号通路： Cytokine-cytokine receptor interaction;Adipocytokine;Amyotrophic lateral sclerosis (ALS);
功能： function:Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.,online information:Clinical information on Enbrel,pharmaceutical:Available under the name Enbrel (Immunex and Wyeth-Ayerst). Used to treat moderate to severe rheumatoid arthritis (RA). Enbrel consist of the extracellular ligand-binding portion of TNFRSF1B linked to an immunoglobulin Fc chain. It binds to TNF-alpha and blocks its interactions with receptors.,PTM:A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by proteolytic processing.,PTM:Phosphorylated; mainly on serine residues and with a very low level on threonine residues.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Binds to TRAF2.,
相关产品： YT4688,KE1250,KA3559C,RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Tumor necrosis factor-binding protein 2]: Secreted.
组织表达： Muscle,PNS,Urine,
tag： hot
科研货号： PLA018446

Hunan UPT Biotechnology Co.,Ltd

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